Depressed mood and reality disturbance correlate with decreased nocturnal melatonin in depressed patients

R. P. Brown, J. H. Kocsis, S. Caroff, J. Amsterdam, A. Winokur, P. Stokes, A. Frazer

Research output: Contribution to journalArticlepeer-review

43 Scopus citations

Abstract

ABSTRACT: The authors measured serum samples of melatonin at 11:00 p.m. in 28 patients suffering from major depression. Melatonin secretion was inversely correlated with the depressed mood and reality disturbance factors of the Hamilton Depression Scale. These results are consistent with previous reports of low melatonin syndrome in a subgroup of depressed patients.

Original languageEnglish (US)
Pages (from-to)272-275
Number of pages4
JournalActa Psychiatrica Scandinavica
Volume76
Issue number3
DOIs
StatePublished - Sep 1987
Externally publishedYes

Keywords

  • major depressive disorder
  • melatonin

ASJC Scopus subject areas

  • Psychiatry and Mental health

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