Abstract
Although APOBEC3 degradation is the canonical function of HIV-1 Vif, this viral protein also induces potent cell cycle arrest through a newly defined mechanism. Here, we review recent advances in this area and propose that the scope of this activity may go beyond subversion of the host cell cycle.
Original language | English (US) |
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Pages (from-to) | 381-384 |
Number of pages | 4 |
Journal | Trends in Microbiology |
Volume | 29 |
Issue number | 5 |
DOIs | |
State | Published - May 2021 |
Externally published | Yes |
Keywords
- G2/M cell cycle arrest
- HIV-1
- PPP2R5
- Vif
- host–pathogen interaction
ASJC Scopus subject areas
- Microbiology (medical)
- Infectious Diseases
- Virology
- Microbiology