Aneurysmal subarachnoid hemorrhage (aSAH) burdens our society not only because of its associated mortality, morbidity and disability, but also due to the high cost of treatment, rehabilitation and supportive care. After the index aneurysmal bleed, delayed vasospasm (DV) is one of aSAH's most serious complications, because it contributes to a large portion of the associated morbidity, mortality and permanent disability. This chapter will present the evolution of our understanding of aSAH associated DV, including the most up-to-date concepts regarding the anatomical, physiological and molecular alterations associated with this vasculopathy, and diagnostic tools for the detection of DV. Finally, this chapter will focus on the evolution of therapeutics for the prevention and treatment of DV using an evidence-based approach.
|Original language||English (US)|
|Title of host publication||Subarachnoid Hemorrhage: Epidemiology, Management and Long-Term Health Effects|
|Publisher||Nova Science Publishers, Inc.|
|Number of pages||41|
|ISBN (Print)||9781634635288, 9781634634922|
|State||Published - Jan 1 2015|
ASJC Scopus subject areas