Degradation of a cohesin subunit by the N-end rule pathway is essential for chromosome stability

E. Peter M. Candido; H. Rao; F. Uhlmann; K. Nasmyth; A. Varshavsky

Degradation of a cohesin subunit by the N-end rule pathway is essential for chromosome stability

E. Peter M. Candido, H. Rao, F. Uhlmann, K. Nasmyth, A. Varshavsky

Research output: Contribution to journal › Review article › peer-review

Abstract

This article demonstrates that the N-end rule pathway of ubiquitin-dependent proteolysis is required for degradation of a subunit of cohesin, a protein which functions to keep sister chromatids together at metaphase.

Original language	English (US)
Pages (from-to)	715-719
Number of pages	5
Journal	Chemtracts
Volume	14
Issue number	13
State	Published - Dec 1 2001
Externally published	Yes

ASJC Scopus subject areas

Chemistry(all)
Biochemistry
Molecular Biology

Cite this

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title = "Degradation of a cohesin subunit by the N-end rule pathway is essential for chromosome stability",

abstract = "This article demonstrates that the N-end rule pathway of ubiquitin-dependent proteolysis is required for degradation of a subunit of cohesin, a protein which functions to keep sister chromatids together at metaphase.",

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T1 - Degradation of a cohesin subunit by the N-end rule pathway is essential for chromosome stability

AU - Candido, E. Peter M.

AU - Rao, H.

AU - Uhlmann, F.

AU - Nasmyth, K.

AU - Varshavsky, A.

PY - 2001/12/1

Y1 - 2001/12/1

N2 - This article demonstrates that the N-end rule pathway of ubiquitin-dependent proteolysis is required for degradation of a subunit of cohesin, a protein which functions to keep sister chromatids together at metaphase.

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AN - SCOPUS:0035715521

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JO - Chemtracts

JF - Chemtracts

IS - 13

ER -

Degradation of a cohesin subunit by the N-end rule pathway is essential for chromosome stability

Abstract

ASJC Scopus subject areas

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