Degradation of a cohesin subunit by the N-end rule pathway is essential for chromosome stability

E. Peter M. Candido, H. Rao, F. Uhlmann, K. Nasmyth, A. Varshavsky

Research output: Contribution to journalReview article

Abstract

This article demonstrates that the N-end rule pathway of ubiquitin-dependent proteolysis is required for degradation of a subunit of cohesin, a protein which functions to keep sister chromatids together at metaphase.

Original languageEnglish (US)
Pages (from-to)715-719
Number of pages5
JournalChemtracts
Volume14
Issue number13
Publication statusPublished - Dec 1 2001

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ASJC Scopus subject areas

  • Chemistry(all)
  • Biochemistry
  • Molecular Biology

Cite this

Candido, E. P. M., Rao, H., Uhlmann, F., Nasmyth, K., & Varshavsky, A. (2001). Degradation of a cohesin subunit by the N-end rule pathway is essential for chromosome stability. Chemtracts, 14(13), 715-719.