Abstract
Porous poly(lactic-glycolic) acid (PLG) implants were fabricated using a modified salt-leaching technique. The in vitro degradation characteristics of these implants were then examined over 8 week period. The increase in dimensions of the implants between weeks 3 and 4 was due to polymer swelling. With time, this increase was overtaken by a loss in dimensions due to mass loss, which increased significantly after week 4. The implants exhibited a high level of degradation by week 8. The fabrication technique yielded highly porous implants with significant permeability. These characteristics make such implants ideal candidates for use as scaffolds for repair or regeneration of tissues.
| Original language | English (US) |
|---|---|
| Title of host publication | Southern Biomedical Engineering Conference - Proceedings |
| Place of Publication | Piscataway, NJ, United States |
| Publisher | IEEE |
| Pages | 18 |
| Number of pages | 1 |
| State | Published - 1998 |
| Event | Proceedings of the 1998 17th Southern Biomedical Engineering Conference - San Antonio, TX, USA Duration: Feb 6 1998 → Feb 8 1998 |
Other
| Other | Proceedings of the 1998 17th Southern Biomedical Engineering Conference |
|---|---|
| City | San Antonio, TX, USA |
| Period | 2/6/98 → 2/8/98 |
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ASJC Scopus subject areas
- Engineering(all)
Cite this
Degradation kinetics of a high porosity biodegradable scaffold. / McKinney, J. S.; Athanasiou, K. A.; Agrawal, C. M.
Southern Biomedical Engineering Conference - Proceedings. Piscataway, NJ, United States : IEEE, 1998. p. 18.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - Degradation kinetics of a high porosity biodegradable scaffold
AU - McKinney, J. S.
AU - Athanasiou, K. A.
AU - Agrawal, C. M.
PY - 1998
Y1 - 1998
N2 - Porous poly(lactic-glycolic) acid (PLG) implants were fabricated using a modified salt-leaching technique. The in vitro degradation characteristics of these implants were then examined over 8 week period. The increase in dimensions of the implants between weeks 3 and 4 was due to polymer swelling. With time, this increase was overtaken by a loss in dimensions due to mass loss, which increased significantly after week 4. The implants exhibited a high level of degradation by week 8. The fabrication technique yielded highly porous implants with significant permeability. These characteristics make such implants ideal candidates for use as scaffolds for repair or regeneration of tissues.
AB - Porous poly(lactic-glycolic) acid (PLG) implants were fabricated using a modified salt-leaching technique. The in vitro degradation characteristics of these implants were then examined over 8 week period. The increase in dimensions of the implants between weeks 3 and 4 was due to polymer swelling. With time, this increase was overtaken by a loss in dimensions due to mass loss, which increased significantly after week 4. The implants exhibited a high level of degradation by week 8. The fabrication technique yielded highly porous implants with significant permeability. These characteristics make such implants ideal candidates for use as scaffolds for repair or regeneration of tissues.
UR - http://www.scopus.com/inward/record.url?scp=0031675163&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0031675163&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:0031675163
SP - 18
BT - Southern Biomedical Engineering Conference - Proceedings
PB - IEEE
CY - Piscataway, NJ, United States
ER -