Abstract
We describe a family in which several members had osteogenesis imperfecta (OI) and/or were positive for HLA-B27. The proband, who had ankylosing spondylitis and OI, had severe osteoporosis with fractures continuing to occur in the late teens. Bone mineral densily measurements in 5 family members and the proband, revealed more severe osteoporosis in those with positive HLA-B27.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 320-324 |
| Number of pages | 5 |
| Journal | Journal of Rheumatology |
| Volume | 20 |
| Issue number | 2 |
| State | Published - 1993 |
Keywords
- HLA-B27
- ankylosing spondylitis
- osteogenesis imperfecta
- osteoporosis
ASJC Scopus subject areas
- Rheumatology
- Immunology and Allergy
- Immunology