Decreased bone mineral density in HLA-B27 positive members of a family with osteogenesis imperfecta

A. Escalante, T. D. Beardmore

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

We describe a family in which several members had osteogenesis imperfecta (OI) and/or were positive for HLA-B27. The proband, who had ankylosing spondylitis and OI, had severe osteoporosis with fractures continuing to occur in the late teens. Bone mineral densily measurements in 5 family members and the proband, revealed more severe osteoporosis in those with positive HLA-B27.

Original languageEnglish (US)
Pages (from-to)320-324
Number of pages5
JournalJournal of Rheumatology
Volume20
Issue number2
StatePublished - Jan 1 1993

Keywords

  • HLA-B27
  • ankylosing spondylitis
  • osteogenesis imperfecta
  • osteoporosis

ASJC Scopus subject areas

  • Rheumatology
  • Immunology and Allergy
  • Immunology

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