Abstract
Background: During the COVID-19 pandemic, decreased volumes of stroke admissions and mechanical thrombectomy were reported. The study's objective was to examine whether subarachnoid haemorrhage (SAH) hospitalisations and ruptured aneurysm coiling interventions demonstrated similar declines. Methods: We conducted a cross-sectional, retrospective, observational study across 6 continents, 37 countries and 140 comprehensive stroke centres. Patients with the diagnosis of SAH, aneurysmal SAH, ruptured aneurysm coiling interventions and COVID-19 were identified by prospective aneurysm databases or by International Classification of Diseases, 10th Revision, codes. The 3-month cumulative volume, monthly volumes for SAH hospitalisations and ruptured aneurysm coiling procedures were compared for the period before (1 year and immediately before) and during the pandemic, defined as 1 March-31 May 2020. The prior 1-year control period (1 March-31 May 2019) was obtained to account for seasonal variation. Findings: There was a significant decline in SAH hospitalisations, with 2044 admissions in the 3 months immediately before and 1585 admissions during the pandemic, representing a relative decline of 22.5% (95% CI -24.3% to -20.7%, p<0.0001). Embolisation of ruptured aneurysms declined with 1170-1035 procedures, respectively, representing an 11.5% (95%CI -13.5% to -9.8%, p=0.002) relative drop. Subgroup analysis was noted for aneurysmal SAH hospitalisation decline from 834 to 626 hospitalisations, a 24.9% relative decline (95% CI -28.0% to -22.1%, p<0.0001). A relative increase in ruptured aneurysm coiling was noted in low coiling volume hospitals of 41.1% (95% CI 32.3% to 50.6%, p=0.008) despite a decrease in SAH admissions in this tertile. Interpretation: There was a relative decrease in the volume of SAH hospitalisations, aneurysmal SAH hospitalisations and ruptured aneurysm embolisations during the COVID-19 pandemic. These findings in SAH are consistent with a decrease in other emergencies, such as stroke and myocardial infarction.
| Original language | English (US) |
|---|---|
| Article number | 000695 |
| Journal | Stroke and Vascular Neurology |
| DOIs | |
| State | Accepted/In press - 2021 |
Keywords
- Aneurysm
- coil
- haemorrhage
- infection
- subarachnoid
ASJC Scopus subject areas
- Clinical Neurology
- Cardiology and Cardiovascular Medicine
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Decline in subarachnoid haemorrhage volumes associated with the first wave of the COVID-19 pandemic. / Nguyen, Thanh N.; Haussen, Diogo C.; Qureshi, Muhammad M.; Yamagami, Hiroshi; Fujinaka, Toshiyuki; Mansour, Ossama Y.; Abdalkader, Mohamad; Frankel, Michael; Qiu, Zhongming; Taylor, Allan; Lylyk, Pedro; Eker, Omer F.; Mechtouff, Laura; Piotin, Michel; Lima, Fabricio Oliveira; Mont'alverne, Francisco; Izzath, Wazim; Sakai, Nobuyuki; Mohammaden, Mahmoud; Al-Bayati, Alhamza R.; Renieri, Leonardo; Mangiafico, Salvatore; Ozretic, David; Chalumeau, Vanessa; Ahmad, Saima; Rashid, Umair; Hussain, Syed Irteza; John, Seby; Griffin, Emma; Thornton, John; Fiorot, Jose Antonio; Rivera, Rodrigo; Hammami, Nadia; Cervantes-Arslanian, Anna M.; Dasenbrock, Hormuzdiyar H.; Vu, Huynh Le; Nguyen, Viet Quy; Hetts, Steven; Bourcier, Romain; Guile, Romain; Walker, Melanie; Sharma, Malveeka; Frei, Don; Jabbour, Pascal; Herial, Nabeel; Al-Mufti, Fawaz; Ozdemir, Atilla Ozcan; Aykac, Ozlem; Gandhi, Dheeraj; Chugh, Chandril; Matouk, Charles; Lavoie, Pascale; Edgell, Randall; Beer-Furlan, Andre; Chen, Michael; Killer-Oberpfalzer, Monika; Pereira, Vitor Mendes; Nicholson, Patrick; Huded, Vikram; Ohara, Nobuyuki; Watanabe, Daisuke; Shin, Dong Hun; Magalhaes, Pedro S.C.; Kikano, Raghid; Ortega-Gutierrez, Santiago; Farooqui, Mudassir; Abou-Hamden, Amal; Amano, Tatsuo; Yamamoto, Ryoo; Weeks, Adrienne; Cora, Elena A.; Sivan-Hoffmann, Rotem; Crosa, Roberto; Möhlenbruch, Markus; Nagel, Simon; Al-Jehani, Hosam; Sheth, Sunil A.; Lopez Rivera, Victor S.; Siegler, James E.; Sani, Achmad Fidaus; Puri, Ajit S.; Kuhn, Anna Luisa; Bernava, Gianmarco; MacHi, Paolo; Abud, Daniel G.; Pontes-Neto, Octavio M.; Wakhloo, Ajay K.; Voetsch, Barbara; Raz, Eytan; Yaghi, Shadi; Mehta, Brijesh P.; Kimura, Naoto; Murakami, Mamoru; Lee, Jin Soo; Hong, Ji Man; Fahed, Robert; Walker, Gregory; Hagashi, Eiji; Cordina, Steve M.; Roh, Hong Gee; Wong, Ken; Arenillas, Juan F.; Martinez-Galdamez, Mario; Blasco, Jordi; Rodriguez Vasquez, Alejandro; Fonseca, Luisa; Silva, M. Luis; Wu, Teddy Y.; John, Simon; Brehm, Alex; Psychogios, Marios; Mack, William J.; Tenser, Matthew; Todaka, Tatemi; Fujimura, Miki; Novakovic, Roberta; Deguchi, Jun; Sugiura, Yuri; Tokimura, Hiroshi; Khatri, Rakesh; Kelly, Michael; Peeling, Lissa; Murayama, Yuichi; Winters, Hugh Stephen; Wong, Johnny; Teleb, Mohamed; Payne, Jeremy; Fukuda, Hiroki; Miyake, Kosuke; Shimbo, Junsuke; Sugimura, Yusuke; Uno, Masaaki; Takenobu, Yohei; Matsumaru, Yuji; Yamada, Satoshi; Kono, Ryuhei; Kanamaru, Takuya; Morimoto, Masafumi; Iida, Junichi; Saini, Vasu; Yavagal, Dileep; Bushnaq, Saif; Huang, Wenguo; Linfante, Italo; Kirmani, Jawad; Liebeskind, David S.; Szeder, Viktor; Shah, Ruchir; Devlin, Thomas G.; Birnbaum, Lee; Luo, Jun; Churojana, Anchalee; Masoud, Hesham E.; Lopez, Carlos Ynigo; Steinfort, Brendan; Ma, Alice; Hassan, Ameer E.; Al Hashmi, Amal; McDermott, Mollie; Mokin, Maxim; Chebl, Alex; Kargiotis, Odysseas; Tsivgoulis, Georgios; Morris, Jane G.; Eskey, Clifford J.; Thon, Jesse; Rebello, Leticia; Altschul, Dorothea; Cornett, Oriana; Singh, Varsha; Pandian, Jeyaraj; Kulkarni, Anirudh; Lavados, Pablo M.; Olavarria, Veronica V.; Todo, Kenichi; Yamamoto, Yuki; Silva, Gisele Sampaio; Geyik, Serdar; Johann, Jasmine; Multani, Sumeet; Kaliaev, Artem; Sonoda, Kazutaka; Hashimoto, Hiroyuki; Alhazzani, Adel; Chung, David Y.; Mayer, Stephan A.; Fifi, Johanna T.; Hill, Michael D.; Zhang, Hao; Yuan, Zhengzhou; Shang, Xianjin; Castonguay, Alicia C.; Gupta, Rishi; Jovin, Tudor G.; Raymond, Jean; Zaidat, Osama O.; Nogueira, Raul G.
In: Stroke and Vascular Neurology, 2021.Research output: Contribution to journal › Article › peer-review
}
TY - JOUR
T1 - Decline in subarachnoid haemorrhage volumes associated with the first wave of the COVID-19 pandemic
AU - Nguyen, Thanh N.
AU - Haussen, Diogo C.
AU - Qureshi, Muhammad M.
AU - Yamagami, Hiroshi
AU - Fujinaka, Toshiyuki
AU - Mansour, Ossama Y.
AU - Abdalkader, Mohamad
AU - Frankel, Michael
AU - Qiu, Zhongming
AU - Taylor, Allan
AU - Lylyk, Pedro
AU - Eker, Omer F.
AU - Mechtouff, Laura
AU - Piotin, Michel
AU - Lima, Fabricio Oliveira
AU - Mont'alverne, Francisco
AU - Izzath, Wazim
AU - Sakai, Nobuyuki
AU - Mohammaden, Mahmoud
AU - Al-Bayati, Alhamza R.
AU - Renieri, Leonardo
AU - Mangiafico, Salvatore
AU - Ozretic, David
AU - Chalumeau, Vanessa
AU - Ahmad, Saima
AU - Rashid, Umair
AU - Hussain, Syed Irteza
AU - John, Seby
AU - Griffin, Emma
AU - Thornton, John
AU - Fiorot, Jose Antonio
AU - Rivera, Rodrigo
AU - Hammami, Nadia
AU - Cervantes-Arslanian, Anna M.
AU - Dasenbrock, Hormuzdiyar H.
AU - Vu, Huynh Le
AU - Nguyen, Viet Quy
AU - Hetts, Steven
AU - Bourcier, Romain
AU - Guile, Romain
AU - Walker, Melanie
AU - Sharma, Malveeka
AU - Frei, Don
AU - Jabbour, Pascal
AU - Herial, Nabeel
AU - Al-Mufti, Fawaz
AU - Ozdemir, Atilla Ozcan
AU - Aykac, Ozlem
AU - Gandhi, Dheeraj
AU - Chugh, Chandril
AU - Matouk, Charles
AU - Lavoie, Pascale
AU - Edgell, Randall
AU - Beer-Furlan, Andre
AU - Chen, Michael
AU - Killer-Oberpfalzer, Monika
AU - Pereira, Vitor Mendes
AU - Nicholson, Patrick
AU - Huded, Vikram
AU - Ohara, Nobuyuki
AU - Watanabe, Daisuke
AU - Shin, Dong Hun
AU - Magalhaes, Pedro S.C.
AU - Kikano, Raghid
AU - Ortega-Gutierrez, Santiago
AU - Farooqui, Mudassir
AU - Abou-Hamden, Amal
AU - Amano, Tatsuo
AU - Yamamoto, Ryoo
AU - Weeks, Adrienne
AU - Cora, Elena A.
AU - Sivan-Hoffmann, Rotem
AU - Crosa, Roberto
AU - Möhlenbruch, Markus
AU - Nagel, Simon
AU - Al-Jehani, Hosam
AU - Sheth, Sunil A.
AU - Lopez Rivera, Victor S.
AU - Siegler, James E.
AU - Sani, Achmad Fidaus
AU - Puri, Ajit S.
AU - Kuhn, Anna Luisa
AU - Bernava, Gianmarco
AU - MacHi, Paolo
AU - Abud, Daniel G.
AU - Pontes-Neto, Octavio M.
AU - Wakhloo, Ajay K.
AU - Voetsch, Barbara
AU - Raz, Eytan
AU - Yaghi, Shadi
AU - Mehta, Brijesh P.
AU - Kimura, Naoto
AU - Murakami, Mamoru
AU - Lee, Jin Soo
AU - Hong, Ji Man
AU - Fahed, Robert
AU - Walker, Gregory
AU - Hagashi, Eiji
AU - Cordina, Steve M.
AU - Roh, Hong Gee
AU - Wong, Ken
AU - Arenillas, Juan F.
AU - Martinez-Galdamez, Mario
AU - Blasco, Jordi
AU - Rodriguez Vasquez, Alejandro
AU - Fonseca, Luisa
AU - Silva, M. Luis
AU - Wu, Teddy Y.
AU - John, Simon
AU - Brehm, Alex
AU - Psychogios, Marios
AU - Mack, William J.
AU - Tenser, Matthew
AU - Todaka, Tatemi
AU - Fujimura, Miki
AU - Novakovic, Roberta
AU - Deguchi, Jun
AU - Sugiura, Yuri
AU - Tokimura, Hiroshi
AU - Khatri, Rakesh
AU - Kelly, Michael
AU - Peeling, Lissa
AU - Murayama, Yuichi
AU - Winters, Hugh Stephen
AU - Wong, Johnny
AU - Teleb, Mohamed
AU - Payne, Jeremy
AU - Fukuda, Hiroki
AU - Miyake, Kosuke
AU - Shimbo, Junsuke
AU - Sugimura, Yusuke
AU - Uno, Masaaki
AU - Takenobu, Yohei
AU - Matsumaru, Yuji
AU - Yamada, Satoshi
AU - Kono, Ryuhei
AU - Kanamaru, Takuya
AU - Morimoto, Masafumi
AU - Iida, Junichi
AU - Saini, Vasu
AU - Yavagal, Dileep
AU - Bushnaq, Saif
AU - Huang, Wenguo
AU - Linfante, Italo
AU - Kirmani, Jawad
AU - Liebeskind, David S.
AU - Szeder, Viktor
AU - Shah, Ruchir
AU - Devlin, Thomas G.
AU - Birnbaum, Lee
AU - Luo, Jun
AU - Churojana, Anchalee
AU - Masoud, Hesham E.
AU - Lopez, Carlos Ynigo
AU - Steinfort, Brendan
AU - Ma, Alice
AU - Hassan, Ameer E.
AU - Al Hashmi, Amal
AU - McDermott, Mollie
AU - Mokin, Maxim
AU - Chebl, Alex
AU - Kargiotis, Odysseas
AU - Tsivgoulis, Georgios
AU - Morris, Jane G.
AU - Eskey, Clifford J.
AU - Thon, Jesse
AU - Rebello, Leticia
AU - Altschul, Dorothea
AU - Cornett, Oriana
AU - Singh, Varsha
AU - Pandian, Jeyaraj
AU - Kulkarni, Anirudh
AU - Lavados, Pablo M.
AU - Olavarria, Veronica V.
AU - Todo, Kenichi
AU - Yamamoto, Yuki
AU - Silva, Gisele Sampaio
AU - Geyik, Serdar
AU - Johann, Jasmine
AU - Multani, Sumeet
AU - Kaliaev, Artem
AU - Sonoda, Kazutaka
AU - Hashimoto, Hiroyuki
AU - Alhazzani, Adel
AU - Chung, David Y.
AU - Mayer, Stephan A.
AU - Fifi, Johanna T.
AU - Hill, Michael D.
AU - Zhang, Hao
AU - Yuan, Zhengzhou
AU - Shang, Xianjin
AU - Castonguay, Alicia C.
AU - Gupta, Rishi
AU - Jovin, Tudor G.
AU - Raymond, Jean
AU - Zaidat, Osama O.
AU - Nogueira, Raul G.
N1 - Publisher Copyright: © Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.
PY - 2021
Y1 - 2021
N2 - Background: During the COVID-19 pandemic, decreased volumes of stroke admissions and mechanical thrombectomy were reported. The study's objective was to examine whether subarachnoid haemorrhage (SAH) hospitalisations and ruptured aneurysm coiling interventions demonstrated similar declines. Methods: We conducted a cross-sectional, retrospective, observational study across 6 continents, 37 countries and 140 comprehensive stroke centres. Patients with the diagnosis of SAH, aneurysmal SAH, ruptured aneurysm coiling interventions and COVID-19 were identified by prospective aneurysm databases or by International Classification of Diseases, 10th Revision, codes. The 3-month cumulative volume, monthly volumes for SAH hospitalisations and ruptured aneurysm coiling procedures were compared for the period before (1 year and immediately before) and during the pandemic, defined as 1 March-31 May 2020. The prior 1-year control period (1 March-31 May 2019) was obtained to account for seasonal variation. Findings: There was a significant decline in SAH hospitalisations, with 2044 admissions in the 3 months immediately before and 1585 admissions during the pandemic, representing a relative decline of 22.5% (95% CI -24.3% to -20.7%, p<0.0001). Embolisation of ruptured aneurysms declined with 1170-1035 procedures, respectively, representing an 11.5% (95%CI -13.5% to -9.8%, p=0.002) relative drop. Subgroup analysis was noted for aneurysmal SAH hospitalisation decline from 834 to 626 hospitalisations, a 24.9% relative decline (95% CI -28.0% to -22.1%, p<0.0001). A relative increase in ruptured aneurysm coiling was noted in low coiling volume hospitals of 41.1% (95% CI 32.3% to 50.6%, p=0.008) despite a decrease in SAH admissions in this tertile. Interpretation: There was a relative decrease in the volume of SAH hospitalisations, aneurysmal SAH hospitalisations and ruptured aneurysm embolisations during the COVID-19 pandemic. These findings in SAH are consistent with a decrease in other emergencies, such as stroke and myocardial infarction.
AB - Background: During the COVID-19 pandemic, decreased volumes of stroke admissions and mechanical thrombectomy were reported. The study's objective was to examine whether subarachnoid haemorrhage (SAH) hospitalisations and ruptured aneurysm coiling interventions demonstrated similar declines. Methods: We conducted a cross-sectional, retrospective, observational study across 6 continents, 37 countries and 140 comprehensive stroke centres. Patients with the diagnosis of SAH, aneurysmal SAH, ruptured aneurysm coiling interventions and COVID-19 were identified by prospective aneurysm databases or by International Classification of Diseases, 10th Revision, codes. The 3-month cumulative volume, monthly volumes for SAH hospitalisations and ruptured aneurysm coiling procedures were compared for the period before (1 year and immediately before) and during the pandemic, defined as 1 March-31 May 2020. The prior 1-year control period (1 March-31 May 2019) was obtained to account for seasonal variation. Findings: There was a significant decline in SAH hospitalisations, with 2044 admissions in the 3 months immediately before and 1585 admissions during the pandemic, representing a relative decline of 22.5% (95% CI -24.3% to -20.7%, p<0.0001). Embolisation of ruptured aneurysms declined with 1170-1035 procedures, respectively, representing an 11.5% (95%CI -13.5% to -9.8%, p=0.002) relative drop. Subgroup analysis was noted for aneurysmal SAH hospitalisation decline from 834 to 626 hospitalisations, a 24.9% relative decline (95% CI -28.0% to -22.1%, p<0.0001). A relative increase in ruptured aneurysm coiling was noted in low coiling volume hospitals of 41.1% (95% CI 32.3% to 50.6%, p=0.008) despite a decrease in SAH admissions in this tertile. Interpretation: There was a relative decrease in the volume of SAH hospitalisations, aneurysmal SAH hospitalisations and ruptured aneurysm embolisations during the COVID-19 pandemic. These findings in SAH are consistent with a decrease in other emergencies, such as stroke and myocardial infarction.
KW - Aneurysm
KW - coil
KW - haemorrhage
KW - infection
KW - subarachnoid
UR - http://www.scopus.com/inward/record.url?scp=85103441210&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85103441210&partnerID=8YFLogxK
U2 - 10.1136/svn-2020-000695
DO - 10.1136/svn-2020-000695
M3 - Article
AN - SCOPUS:85103441210
JO - Stroke and Vascular Neurology
JF - Stroke and Vascular Neurology
SN - 2059-8688
M1 - 000695
ER -