Day:Night variations of melatonin, 5-hydroxyindole acetic acid, serotonin, serotonin N-acetytransferase, tryptophan, norephinephrine and dopamine in the rabbit pineal gland

George C. Brainard, Susan A. Matthews, Richard W. Steger, Russel J. Reiter, Ricardo H. Asch

Research output: Contribution to journalArticlepeer-review

23 Scopus citations

Abstract

Pineal tryptophan, serotonin, serotonin-N-acetyltransferase (NAT), melatonin, 5-hydroxyindole acetic acid (5HIAA), norephinephrine and dopamine were measured in 5 castrated rabbits each at 11.00, 00.30 and 03.00 hours. The rabbits were housed in an L:D 14:10 (lights on 07.00 hours). Significant day:night variations were found in NAT, melatonin, dopamine and norepinephrine. These results were compared to data concerning rhythms of pineal constituents in other species.

Original languageEnglish (US)
Pages (from-to)1615-1622
Number of pages8
JournalLife Sciences
Volume35
Issue number15
DOIs
StatePublished - Oct 8 1984

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)

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