Dapsone for Recalcitrant Eosinophilic Annular Erythema: A Case Report and Literature Review

Luke Wallis, Robert C. Gilson, Robert T. Gilson

Research output: Contribution to journalArticle

6 Scopus citations

Abstract

Eosinophilic annular erythema (EAE) is a rare entity of unknown etiology that is possibly related to a hypersensitivity reaction and presents as annular erythematous plaques with tissue eosinophilia. It is classified as a figurate erythema with a controversial relationship to Wells syndrome (WS) in the literature, where it is generally considered a separate entity or subset based on clinical and histopathologic differences. EAE typically presents with recurrent, erythematous, arcuate, and annular plaques on the trunk and proximal extremities. The course of the disease is often chronic, recurrent, and relapsing. Responses to treatment are variable but are typically best with systemic steroids and antimalarials. We report a patient refractory to other therapies who had a striking response to dapsone.

Original languageEnglish (US)
Pages (from-to)157-163
Number of pages7
JournalDermatology and Therapy
Volume8
Issue number1
DOIs
StatePublished - Mar 1 2018

Keywords

  • Annular erythema
  • Dapsone
  • Eosinophilia
  • Eosinophilic
  • Treatment resistance
  • Wells syndrome

ASJC Scopus subject areas

  • Dermatology

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