Abstract
Adult extracardiac rhabdomyomas are rare benign mesenchymal tumor arising from skeletal muscle. While they are often located in the larynx and pharynx, the incidence in the parapharyngeal area is extremely rare with only 1 documented cytology case report to date. We report a case of an adult extracardiac rhabdomyoma in the parapharyngeal space diagnosed cytologically with subsequent histologic confirmation. The patient is a 57-year-old man with history of weight loss, hematuria, dysphagia, and airway encroachment. Computerized tomography of his abdomen showed a large left renal mass. While the patient was in the operating room for the resection of his renal mass, a fine-needle aspiration from left the parapharyngeal mass was performed. The smears showed uniform bland polygonal cells with abundant eosinophilic cytoplasm and peripherally located nuclei. Immunohistochemical stains performed on the cell block showed the tumor cells were desmin positive and negative for S-100 and PAX-8, supporting the diagnosis of an adult rhabdomyoma. Subsequent resection of the mass confirmed the diagnosis of an adult extracardiac rhabdomyoma.
| Original language | English (US) |
|---|---|
| Journal | Diagnostic Cytopathology |
| DOIs | |
| State | Accepted/In press - 2017 |
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Keywords
- Adult rhabdomyoma
- Cytology
- Fine needle aspiration
- Parapharyngeal space
ASJC Scopus subject areas
- Pathology and Forensic Medicine
- Histology
Cite this
Cytologic findings of an adult rhabdomyoma in the parapharyngeal space : A report of a case and review of the literature. / Dermawan, Josephine Kamtai; Doxtader, Erika; Chute, Deborah J.; Policarpio-Nicolas, Maria Luisa.
In: Diagnostic Cytopathology, 2017.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Cytologic findings of an adult rhabdomyoma in the parapharyngeal space
T2 - A report of a case and review of the literature
AU - Dermawan, Josephine Kamtai
AU - Doxtader, Erika
AU - Chute, Deborah J.
AU - Policarpio-Nicolas, Maria Luisa
PY - 2017
Y1 - 2017
N2 - Adult extracardiac rhabdomyomas are rare benign mesenchymal tumor arising from skeletal muscle. While they are often located in the larynx and pharynx, the incidence in the parapharyngeal area is extremely rare with only 1 documented cytology case report to date. We report a case of an adult extracardiac rhabdomyoma in the parapharyngeal space diagnosed cytologically with subsequent histologic confirmation. The patient is a 57-year-old man with history of weight loss, hematuria, dysphagia, and airway encroachment. Computerized tomography of his abdomen showed a large left renal mass. While the patient was in the operating room for the resection of his renal mass, a fine-needle aspiration from left the parapharyngeal mass was performed. The smears showed uniform bland polygonal cells with abundant eosinophilic cytoplasm and peripherally located nuclei. Immunohistochemical stains performed on the cell block showed the tumor cells were desmin positive and negative for S-100 and PAX-8, supporting the diagnosis of an adult rhabdomyoma. Subsequent resection of the mass confirmed the diagnosis of an adult extracardiac rhabdomyoma.
AB - Adult extracardiac rhabdomyomas are rare benign mesenchymal tumor arising from skeletal muscle. While they are often located in the larynx and pharynx, the incidence in the parapharyngeal area is extremely rare with only 1 documented cytology case report to date. We report a case of an adult extracardiac rhabdomyoma in the parapharyngeal space diagnosed cytologically with subsequent histologic confirmation. The patient is a 57-year-old man with history of weight loss, hematuria, dysphagia, and airway encroachment. Computerized tomography of his abdomen showed a large left renal mass. While the patient was in the operating room for the resection of his renal mass, a fine-needle aspiration from left the parapharyngeal mass was performed. The smears showed uniform bland polygonal cells with abundant eosinophilic cytoplasm and peripherally located nuclei. Immunohistochemical stains performed on the cell block showed the tumor cells were desmin positive and negative for S-100 and PAX-8, supporting the diagnosis of an adult rhabdomyoma. Subsequent resection of the mass confirmed the diagnosis of an adult extracardiac rhabdomyoma.
KW - Adult rhabdomyoma
KW - Cytology
KW - Fine needle aspiration
KW - Parapharyngeal space
UR - http://www.scopus.com/inward/record.url?scp=85033554904&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85033554904&partnerID=8YFLogxK
U2 - 10.1002/dc.23860
DO - 10.1002/dc.23860
M3 - Article
AN - SCOPUS:85033554904
JO - Diagnostic Cytopathology
JF - Diagnostic Cytopathology
SN - 8755-1039
ER -