Cystic Lesions as a Rare Complication of Deep Brain Stimulation

Vibhash D. Sharma, Alberto R. Bona, Alessandra Mantovani, Svjetlana Miocinovic, Pravin Khemani, Mark P. Goldberg, Kelly D. Foote, Louis A. Whitworth, Shilpa Chitnis, Michael S. Okun

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


DBS is a typically well-tolerated operation for treatment of Parkinson's disease, dystonia, and essential tremor (ET). Complications related to the surgical procedure and implanted hardware may occur. More commonly reported complications include hemorrhage, seizure, confusion, and infection. In this article, we report on a rare, but important, complication of DBS surgery, a brain cyst formation at the tip of the implanted ventralis intermedius nucleus (VIM) DBS lead in 2 patients who underwent the procedure at 2 different centers. The indication for surgery was debilitating ET, and in both cases, there was development of a delayed-onset neurological deficit associated with an internal capsule/thalamic cystic lesion formation located at the tip of the DBS lead. Case 1 presented within a few months post-DBS, whereas case 2 had a 10-mo delay to onset of symptoms. No clinical and radiological signs of infection were observed and both DBS systems were explanted with uneventful recovery.

Original languageEnglish (US)
Pages (from-to)87-90
Number of pages4
JournalMovement Disorders Clinical Practice
Issue number1
StatePublished - Jan 1 2016
Externally publishedYes


  • Complication
  • Cyst
  • Deep brain stimulation

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology


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