Exposure of osteoblasts to cyclic pressure was studied and cellular/molecular responses of functions that were pertinent to new bone formation were monitored. It was found that exposure to cyclic pressure for one hour daily for up to 19 consecutive days induced specific osteoblast responses such as enhanced mRNA expression of alkaline phosphatase. The results provided insight into the cellular/molecular level mechanism that correlated mechanical loading on the skeleton and bone homeostasis.
|Original language||English (US)|
|Number of pages||2|
|Journal||American Society of Mechanical Engineers, Bioengineering Division (Publication) BED|
|State||Published - 2001|
|Event||Proceedings of the 2001 Bioengineering Conference - Snowbird, UT, United States|
Duration: Jun 27 2001 → Jul 1 2001
ASJC Scopus subject areas