Cyclic nucleotides and prostaglandins (PGs) produced by the rabbit oviduct: effects of estrogen treatment

G. Valenzuela, R. Antonini, B. J. Hodgson, D. J. Jones, M. J. Harper

Research output: Contribution to journalArticle

Abstract

Levels of cyclic AMP and cyclic GMP were measured in oviducts of rabbits killed 68 hr after injection of human chorionic gonadotrophin (HCG) to induce ovulation. cAMP and cGMP levels were higher in the isthmus than in the ampulla. Estrogen treatment given at the same time as HCG increased cGMP levels. Levels of PGE and PGF in blood draining the oviduct were low and showed no effect of estrogen treatment at 68 hr after HCG.

Original languageEnglish (US)
Pages (from-to)361-364
Number of pages4
JournalResearch Communications in Chemical Pathology and Pharmacology
Volume17
Issue number2
Publication statusPublished - Dec 1 1977

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ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Toxicology
  • Pharmacology
  • Pharmacology, Toxicology and Pharmaceutics(all)

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