Cyclic loading (vibration) accelerates tooth movement in orthodontic patients: A double-blind, randomized controlled trial

Dubravko Pavlin, Ravikumar Anthony, Vishnu Raj, Peter T. Gakunga

Research output: Contribution to journalArticlepeer-review

47 Scopus citations


This was a parallel, double-blind, prospective, randomized, controlled trial with the objective to assess the effect of a defined low-level cyclic loading on the rate of orthodontic tooth movement. Overall, 45 orthodontic patients were treated with fixed appliances at the UTHSC San Antonio Orthodontic Department. Inclusion criteria were extraction of maxillary first premolars, maximum maxillary posterior anchorage, and at least 3mm of extraction space after initial alignment. The enrolled subjects were randomized into two groups, vibration (n = 23) and control (n = 22) using a third-party computer-generated randomization schedule. All care providers, investigators, and patients were blinded to intervention assignment. Cyclic loading was applied to the vibration group for 20min/day using the AcceleDent® device, which delivered a force of 0.25N (25g) at a frequency of 30Hz. The control group was assigned to the same protocol, but the device could not be activated to vibrate. The average monthly rate of maxillary canine retraction into an extraction space was analyzed in all 45 subjects (ITT group). The mean rate of movement was significantly higher for the AcceleDent® group with 1.16mm/month (95% CI: 0.86-1.46) compared to 0.79mm/month (95% CI: 0.49-1.09) in the control group, with the mean difference of 0.37mm/month (95% CI: 0.07-0.81, P = 0.05). These results showed that low-level cyclic loading of 0.25N at 30Hz increases the rate of tooth movement when applied as an adjunct to orthodontic treatment.

Original languageEnglish (US)
Pages (from-to)187-194
Number of pages8
JournalSeminars in Orthodontics
Issue number3
StatePublished - Sep 1 2015

ASJC Scopus subject areas

  • Orthodontics


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