TY - JOUR
T1 - Cyclic loading (vibration) accelerates tooth movement in orthodontic patients
T2 - A double-blind, randomized controlled trial
AU - Pavlin, Dubravko
AU - Anthony, Ravikumar
AU - Raj, Vishnu
AU - Gakunga, Peter T.
N1 - Funding Information:
Funding, Conflict of Interest: This study was supported by the research grant from the OrthoAccel Technologies, Inc. [(OATI), Bellaire, TX], which was permitted to review this manuscript, but the right to a final decision on the content was exclusively retained by the authors. The corresponding author (D.P.) is a consultant for OATI and had participated in developing the study protocol approved by the FDA. He was blinded to the group assignments and did not participate in either data collection or treatment of any of the enrolled subjects.
Publisher Copyright:
© 2015 The Authors.
Copyright:
Copyright 2015 Elsevier B.V., All rights reserved.
PY - 2015/9/1
Y1 - 2015/9/1
N2 - This was a parallel, double-blind, prospective, randomized, controlled trial with the objective to assess the effect of a defined low-level cyclic loading on the rate of orthodontic tooth movement. Overall, 45 orthodontic patients were treated with fixed appliances at the UTHSC San Antonio Orthodontic Department. Inclusion criteria were extraction of maxillary first premolars, maximum maxillary posterior anchorage, and at least 3mm of extraction space after initial alignment. The enrolled subjects were randomized into two groups, vibration (n = 23) and control (n = 22) using a third-party computer-generated randomization schedule. All care providers, investigators, and patients were blinded to intervention assignment. Cyclic loading was applied to the vibration group for 20min/day using the AcceleDent® device, which delivered a force of 0.25N (25g) at a frequency of 30Hz. The control group was assigned to the same protocol, but the device could not be activated to vibrate. The average monthly rate of maxillary canine retraction into an extraction space was analyzed in all 45 subjects (ITT group). The mean rate of movement was significantly higher for the AcceleDent® group with 1.16mm/month (95% CI: 0.86-1.46) compared to 0.79mm/month (95% CI: 0.49-1.09) in the control group, with the mean difference of 0.37mm/month (95% CI: 0.07-0.81, P = 0.05). These results showed that low-level cyclic loading of 0.25N at 30Hz increases the rate of tooth movement when applied as an adjunct to orthodontic treatment.
AB - This was a parallel, double-blind, prospective, randomized, controlled trial with the objective to assess the effect of a defined low-level cyclic loading on the rate of orthodontic tooth movement. Overall, 45 orthodontic patients were treated with fixed appliances at the UTHSC San Antonio Orthodontic Department. Inclusion criteria were extraction of maxillary first premolars, maximum maxillary posterior anchorage, and at least 3mm of extraction space after initial alignment. The enrolled subjects were randomized into two groups, vibration (n = 23) and control (n = 22) using a third-party computer-generated randomization schedule. All care providers, investigators, and patients were blinded to intervention assignment. Cyclic loading was applied to the vibration group for 20min/day using the AcceleDent® device, which delivered a force of 0.25N (25g) at a frequency of 30Hz. The control group was assigned to the same protocol, but the device could not be activated to vibrate. The average monthly rate of maxillary canine retraction into an extraction space was analyzed in all 45 subjects (ITT group). The mean rate of movement was significantly higher for the AcceleDent® group with 1.16mm/month (95% CI: 0.86-1.46) compared to 0.79mm/month (95% CI: 0.49-1.09) in the control group, with the mean difference of 0.37mm/month (95% CI: 0.07-0.81, P = 0.05). These results showed that low-level cyclic loading of 0.25N at 30Hz increases the rate of tooth movement when applied as an adjunct to orthodontic treatment.
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U2 - 10.1053/j.sodo.2015.06.005
DO - 10.1053/j.sodo.2015.06.005
M3 - Article
AN - SCOPUS:84941023387
VL - 21
SP - 187
EP - 194
JO - Seminars in Orthodontics
JF - Seminars in Orthodontics
SN - 1073-8746
IS - 3
ER -