TY - JOUR
T1 - Cutaneous tumors as the initial presentation of non-T, non-B, nonmyeloid CD4+ CD56+ hematolymphoid malignancy in an adolescent boy
AU - Fass, Jonathan
AU - Tichy, Elizabeth H.
AU - Kraus, Eric W.
AU - Herrick, Jennifer L.
AU - Ehsan, Aamir
AU - Peterson, Joe
AU - Grimwood, Ronald E.
PY - 2005/1/1
Y1 - 2005/1/1
N2 - We describe a 14-year-old Hispanic boy who presented with a 2-month history of enlarging plum-colored cutaneous tumors on his face, trunk, and proximal extremities. Histopathologic examination showed nodular infiltrates of malignant mononuclear cells extending from the superficial dermis to the deep subcutis. Immunohistochemical staining of the biopsy specimen and flow cytometry studies on a bone marrow aspirate revealed a CD4+, CD56+ hematolymphoid tumor that was negative for all other myeloid and lymphoid markers. Based on this information, the patient was diagnosed with the recently described, rare non-T, non-B, nonmyeloid CD4+ CD56+ hematolymphoid malignancy. To our knowledge, this is the youngest patient reported in the literature.
AB - We describe a 14-year-old Hispanic boy who presented with a 2-month history of enlarging plum-colored cutaneous tumors on his face, trunk, and proximal extremities. Histopathologic examination showed nodular infiltrates of malignant mononuclear cells extending from the superficial dermis to the deep subcutis. Immunohistochemical staining of the biopsy specimen and flow cytometry studies on a bone marrow aspirate revealed a CD4+, CD56+ hematolymphoid tumor that was negative for all other myeloid and lymphoid markers. Based on this information, the patient was diagnosed with the recently described, rare non-T, non-B, nonmyeloid CD4+ CD56+ hematolymphoid malignancy. To our knowledge, this is the youngest patient reported in the literature.
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U2 - 10.1111/j.1525-1470.2005.22104.x
DO - 10.1111/j.1525-1470.2005.22104.x
M3 - Article
C2 - 15660891
AN - SCOPUS:12944314892
VL - 22
SP - 19
EP - 22
JO - Pediatric Dermatology
JF - Pediatric Dermatology
SN - 0736-8046
IS - 1
ER -