Cutaneous tumors as the initial presentation of non-T, non-B, nonmyeloid CD4+ CD56+ hematolymphoid malignancy in an adolescent boy

Jonathan Fass, Elizabeth H. Tichy, Eric W. Kraus, Jennifer L. Herrick, Aamir Ehsan, Joe Peterson, Ronald E. Grimwood

Research output: Contribution to journalArticle

4 Scopus citations


We describe a 14-year-old Hispanic boy who presented with a 2-month history of enlarging plum-colored cutaneous tumors on his face, trunk, and proximal extremities. Histopathologic examination showed nodular infiltrates of malignant mononuclear cells extending from the superficial dermis to the deep subcutis. Immunohistochemical staining of the biopsy specimen and flow cytometry studies on a bone marrow aspirate revealed a CD4+, CD56+ hematolymphoid tumor that was negative for all other myeloid and lymphoid markers. Based on this information, the patient was diagnosed with the recently described, rare non-T, non-B, nonmyeloid CD4+ CD56+ hematolymphoid malignancy. To our knowledge, this is the youngest patient reported in the literature.

Original languageEnglish (US)
Pages (from-to)19-22
Number of pages4
JournalPediatric Dermatology
Issue number1
Publication statusPublished - Jan 1 2005


ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Dermatology

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