Cutaneous sarcoidosis masquerading as chronic cutaneous lupus erythematosus - Case report

Marjon Vatanchi, Kaivon Sobhani, Valerie T. Fisher, Jeffrey J. Meffert

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Background: Sarcoidosis is a multisystemic granulomatous disease of unknown origin. Chronic cutaneous lupus erythematosus (CCLE) is an autoimmune disease that is associated with autoantibody production and T-cell dysfunction. Cutaneous manifestations of sarcoidosis may mimic CCLE and vice versa making it difficult to reach a diagnosis clinically. Case presentation: We present a case of a 57-year-old woman with long-standing sarcoidosis who presented to clinic with diffuse painful plaques that were very distinct and suggestive of CCLE. She had a family history of both sarcoidosis and CCLE. The patient was immediately started on topical corticosteroids and oral hydroxychloroquine. Skin biopsy and the absence of direct immunofluorescence confirmed a skin manifestation of her previously diagnosed sarcoidosis, despite the clinical morphology favoring classic CCLE. Conclusion: Sarcoidosis may have diverse manifestations and may mimic other disease processes. A detailed history along with a low threshold for biopsy is important for determining a diagnosis.

Original languageEnglish (US)
Article number14
JournalBMC Dermatology
Volume16
Issue number1
DOIs
StatePublished - Sep 20 2016

Keywords

  • CCLE
  • Chronic cutaneous lupus erythematosus
  • DLE
  • Discoid lupus
  • Lupus
  • Sarcoidosis

ASJC Scopus subject areas

  • Dermatology

Fingerprint Dive into the research topics of 'Cutaneous sarcoidosis masquerading as chronic cutaneous lupus erythematosus - Case report'. Together they form a unique fingerprint.

Cite this