Cutaneous infection caused by Cylindrocarpon lichenicola in a patient with acute myelogenous leukemia

P. C. Iwen, S. R. Tarantolo, D. A. Sutton, M. G. Rinaldi, S. H. Hinrichs

Research output: Contribution to journalArticlepeer-review

16 Scopus citations


Cylindrocarpon lichenicola is a saprophytic soil fungus which has rarely been associated with human disease. We report the first case of localized invasive cutaneous infection caused by this fungus in a 53-year-old male from the rural midwestern United States with relapsed acute myelogenous leukemia. On admission for induction chemotherapy, the patient was noted to have an abrasive laceration between the fourth and fifth metacarpophalangeal joints and on the dorsum of the right hand, which progressed to frank ulceration following chemotherapy. A biopsy provided an initial diagnosis of an invasive fungal infection consistent with aspergillosis based on the histopathological appearance of the mold in tissue. Multiple positive fungal cultures which were obtained from the biopsied tissue were subsequently identified by microscopic and macroscopic characteristics to be C. lichenicola. The infection resolved following marrow regeneration, aggressive debridement of the affected tissue, and treatment with amphotericin B. This case extends the conditions associated with invasive disease caused by C. lichenicola.

Original languageEnglish (US)
Pages (from-to)3375-3378
Number of pages4
JournalJournal of clinical microbiology
Issue number9
StatePublished - 2000
Externally publishedYes

ASJC Scopus subject areas

  • Microbiology (medical)


Dive into the research topics of 'Cutaneous infection caused by Cylindrocarpon lichenicola in a patient with acute myelogenous leukemia'. Together they form a unique fingerprint.

Cite this