Current directions in tau research: Highlights from Tau 2020

Claire Sexton, Heather Snyder, Dirk Beher, Adam L. Boxer, Pat Brannelly, Jean Pierre Brion, Luc Buée, Angela M. Cacace, Gaël Chételat, Martin Citron, Sarah L. DeVos, Kristophe Diaz, Howard H. Feldman, Bess Frost, Alison M. Goate, Michael Gold, Bradley Hyman, Keith Johnson, Celeste M. Karch, Diana R. KerwinWalter J. Koroshetz, Irene Litvan, Huw R. Morris, Catherine J. Mummery, James Mutamba, Marc C. Patterson, Yakeel T. Quiroz, Gil D. Rabinovici, Amy Rommel, Melanie B. Shulman, Leticia M. Toledo-Sherman, Stacie Weninger, Kristin R. Wildsmith, Susan L. Worley, Maria C. Carrillo

Research output: Contribution to journalReview articlepeer-review

Abstract

Studies supporting a strong association between tau deposition and neuronal loss, neurodegeneration, and cognitive decline have heightened the allure of tau and tau-related mechanisms as therapeutic targets. In February 2020, leading tau experts from around the world convened for the first-ever Tau2020 Global Conference in Washington, DC, co-organized and cosponsored by the Rainwater Charitable Foundation, the Alzheimer's Association, and CurePSP. Representing academia, industry, government, and the philanthropic sector, presenters and attendees discussed recent advances and current directions in tau research. The meeting provided a unique opportunity to move tau research forward by fostering global partnerships among academia, industry, and other stakeholders and by providing support for new drug discovery programs, groundbreaking research, and emerging tau researchers. The meeting also provided an opportunity for experts to present critical research-advancing tools and insights that are now rapidly accelerating the pace of tau research.

Keywords

  • Alzheimer's
  • biomarkers
  • neurodegeneration
  • tau
  • therapeutics

ASJC Scopus subject areas

  • Epidemiology
  • Health Policy
  • Developmental Neuroscience
  • Clinical Neurology
  • Geriatrics and Gerontology
  • Psychiatry and Mental health
  • Cellular and Molecular Neuroscience

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