Cunninghamella echinulata causing fatally invasive fungal sinusitis

Robert E. LeBlanc, Zina Meriden, Deanna A. Sutton, Elizabeth H. Thompson, Dionissios Neofytos, Sean X. Zhang

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

We report a fatal case of invasive fungal sinusitis caused by Cunninghamella echinulata in a febrile, neutropenic 15-year-old male with relapsing acute leukemia. The isolate was recovered from a nasal biopsy from the right middle meatus, and microscopic examination of the tissue revealed angioinvasion and necrosis. Human infection caused by this organism has not been well documented; however, this report alerts us to its life-threatening potential.

Original languageEnglish (US)
Pages (from-to)506-509
Number of pages4
JournalDiagnostic Microbiology and Infectious Disease
Volume76
Issue number4
DOIs
StatePublished - Aug 1 2013

Keywords

  • Angioinvasion
  • Cunninghamella
  • Cunninghamella echinulata
  • Febrile neutropenia
  • Filamentous fungi
  • Invasive fungal infection
  • Leukemia
  • Sinusitis
  • Zygomycetes

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

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