CSF1R inhibitor JNJ-40346527 attenuates microglial proliferation and neurodegeneration in P301S mice

Renzo Mancuso, Gemma Fryatt, Madeleine Cleal, Juliane Obst, Elena Pipi, Jimena Monzón-Sandoval, Elena Ribe, Laura Winchester, Caleb Webber, Alejo Nevado, Tom Jacobs, Nigel Austin, Clara Theunis, Karolien Grauwen, Eva Daniela Ruiz, Amrit Mudher, Marta Vicente-Rodriguez, Christine A. Parker, Camilla Simmons, Diana CashJill Richardson, Declan N.C. Jones, Simon Lovestone, Diego Gómez-Nicola, V. Hugh Perry, Edward T. Bullmore, Junaid Bhatti, Samuel J. Chamberlain, Marta M. Correia, Anna L. Crofts, Amber Dickinson, Andrew C. Foster, Manfred G. Kitzbichler, Clare Knight, Mary Ellen Lynall, Christina Maurice, Ciara O'Donnell, Linda J. Pointon, Peter St George Hyslop, Lorinda Turner, Petra Vertes, Barry Widmer, Guy B. Williams, B. Paul Morgan, Claire A. Leckey, Angharad R. Morgan, Caroline O'Hagan, Samuel Touchard, Jonathan Cavanagh, Catherine Deith, Scott Farmer, John McClean, Alison McColl, Andrew McPherson, Paul Scouller, Murray Sutherland, H. W.G.M. Boddeke, Jill C. Richardson, Shahid Khan, Phil Murphy, Christine A. Parker, Jai Patel, Declan Jones, Peter De Boer, John Kemp, Wayne C. Drevets, Jeffrey S. Nye, Gayle Wittenberg, John Isaac, Anindya Bhattacharya, Nick Carruthers, Hartmuth Kolb, Carmine M. Pariante, Federico Turkheimer, Gareth J. Barker, Heidi Byrom, Diana Cash, Annamaria Cattaneo, Antony Gee, Caitlin Hastings, Nicole Mariani, Anna McLaughlin, Valeria Mondelli, Maria Nettis, Naghmeh Nikkheslat, Karen Randall, Hannah Sheridan, Camilla Simmons, Nisha Singh, Victoria Van Loo, Marta Vicente-Rodriguez, Tobias C. Wood, Courtney Worrell, Zuzanna Zajkowska, Niels Plath, Jan Egebjerg, Hans Eriksson, Francois Gastambide, Karen Husted Adams, Ross Jeggo, Christian Thomsen, Jan Torleif Pederson, Brian Campbell, Thomas Möller, Bob Nelson, Stevin Zorn, Jason O'Connor, Mary Jane Attenburrow, Alison Baird, Jithen Benjamin, Stuart Clare, Philip Cowen, I. Shu Huang, Samuel Hurley, Helen Jones, Francisca Mada, Alejo Nevado-Holgado, Akintayo Oladejo, Elena Ribe, Katy Smith, Anviti Vyas, Zoe Hughes, Rita Balice-Gordon, James Duerr, Justin R. Piro, Jonathan Sporn, V. Hugh Perry, Madeleine Cleal, Gemma Fryatt, Diego Gomez-Nicola, Renzo Mancuso, Richard Reynolds, Neil A. Harrison, Mara Cercignani, Charlotte L. Clarke, Elizabeth Hoskins, Charmaine Kohn, Rosemary Murray, Lauren Wilcock, Dominika Wlazly, Howard Mount

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Pharmacology, Toxicology and Pharmaceutical Science

Neuroscience