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Crystal Structure of a Human Autoimmune Complex between IgM Rheumatoid Factor RF61 and IgG1 Fc Reveals a Novel Epitope and Evidence for Affinity Maturation

  • Stephane Duquerroy
  • , Enrico A. Stura
  • , Stéphane Bressanelli
  • , Stella M. Fabiane
  • , Marie C. Vaney
  • , Dennis Beale
  • , Maureen Hamon
  • , Paolo Casali
  • , Felix A. Rey
  • , Brian J. Sutton
  • , Michael J. Taussig

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Immunology and Microbiology

Biochemistry, Genetics and Molecular Biology