Cryogenic damage to peripheral nerves and blood vessels in the rat

A. R. Marsland, S. Ramamurthy, J. Barnes

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The effects of cryogenic injury on femoral blood vessels and nerves were studied in 28 rats. The femoral neurovascular bundles were dissected out bilaterally and the vessels and nerves subjected to cryogenic injury. The rats were sacrificed at intervals of up to 2 weeks. Damage to the nerves and to a number of femoral vessels was severe and included necrosis and thrombus formation. The results indicate that significant vascular damage can occur during cryothcrapy, and the possible complications of this should be considered.

Original languageEnglish (US)
Pages (from-to)555-558
Number of pages4
JournalBritish Journal of Anaesthesia
Issue number6
Publication statusPublished - Jun 1983


ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

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