Criticial limb ischemia: epidemiology.

Mark G. Davies

Research output: Contribution to journalReview articlepeer-review

56 Scopus citations


Critical limb ischemia is found in 12% of the U.S. adult population. Its clinical presentation varies from no symptoms to intermittent claudication, atypical leg pain, rest pain, ischemic ulcers, or gangrene. Those with critical limb ischemia have a high incidence of cardiovascular comorbidities that reflect a significant systemic atherosclerotic burden; they have increased functional impairment and increased rates of functional decline compared with persons without critical limb ischemia. Interventions for critical limb ischemia and the impact of major amputation have a significant social and economic impact. At 1 year, 25% of patients will be dead, 30% will have undergone amputation, and only 45% will remain alive with both limbs. At 5 years, more than 60% of patients with critical limb ischemia will be dead.

Original languageEnglish (US)
Pages (from-to)10-14
Number of pages5
JournalUnknown Journal
Issue number4
StatePublished - 2012
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)


Dive into the research topics of 'Criticial limb ischemia: epidemiology.'. Together they form a unique fingerprint.

Cite this