Craniofacial Tissue Bioengineering and Regeneration by Endogenous Stem Cells

Nan Jiang; Mo Chen; Chang Hun Lee; Jian Zhou; Mildred C. Embree; Kimi Kong; Choko Cho; Avital Mendelson; Ying Zheng; Hemin Nie; Jeremy J. Mao

doi:10.1002/9781118498026.ch20

Craniofacial Tissue Bioengineering and Regeneration by Endogenous Stem Cells

Nan Jiang, Mo Chen, Chang Hun Lee, Jian Zhou, Mildred C. Embree, Kimi Kong, Choko Cho, Avital Mendelson, Ying Zheng, Hemin Nie, Jeremy J. Mao

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Directed movement of stem cells is crucial not only for organogenesis during development, but also for tissue regeneration in adult life. This chapter presents examples of stem cell migration and recruitment and the application of cell homing in orofacial regeneration. Cell homing refers to the recruitment of endogenous cells, including stem and progenitor cells, into a wound. Homing can be local and/or systemic. Whereas cell homing via circulation has contributed a great deal to the knowledge of pathogenesis of diverse diseases, including infections and tumor metastasis, we understand little of how to immobilize and direct cell homing in tissue regeneration. Stem and progenitor cells are highlighted to demonstrate their migration, lineage commitment, and potential roles in wound healing.

Original language	English (US)
Title of host publication	Stem Cells in Craniofacial Development and Regeneration
Publisher	John Wiley and Sons
Pages	367-378
Number of pages	12
ISBN (Print)	9781118279236
DOIs	https://doi.org/10.1002/9781118498026.ch20
State	Published - Mar 26 2013
Externally published	Yes

Keywords

Cell homing
Cell migration
Craniofacial tissue bioengineering
Endogenous stem cells

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)

Access to Document

10.1002/9781118498026.ch20

Cite this

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abstract = "Directed movement of stem cells is crucial not only for organogenesis during development, but also for tissue regeneration in adult life. This chapter presents examples of stem cell migration and recruitment and the application of cell homing in orofacial regeneration. Cell homing refers to the recruitment of endogenous cells, including stem and progenitor cells, into a wound. Homing can be local and/or systemic. Whereas cell homing via circulation has contributed a great deal to the knowledge of pathogenesis of diverse diseases, including infections and tumor metastasis, we understand little of how to immobilize and direct cell homing in tissue regeneration. Stem and progenitor cells are highlighted to demonstrate their migration, lineage commitment, and potential roles in wound healing.",

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AU - Jiang, Nan

AU - Chen, Mo

AU - Lee, Chang Hun

AU - Zhou, Jian

AU - Embree, Mildred C.

AU - Kong, Kimi

AU - Cho, Choko

AU - Mendelson, Avital

AU - Zheng, Ying

AU - Nie, Hemin

AU - Mao, Jeremy J.

PY - 2013/3/26

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N2 - Directed movement of stem cells is crucial not only for organogenesis during development, but also for tissue regeneration in adult life. This chapter presents examples of stem cell migration and recruitment and the application of cell homing in orofacial regeneration. Cell homing refers to the recruitment of endogenous cells, including stem and progenitor cells, into a wound. Homing can be local and/or systemic. Whereas cell homing via circulation has contributed a great deal to the knowledge of pathogenesis of diverse diseases, including infections and tumor metastasis, we understand little of how to immobilize and direct cell homing in tissue regeneration. Stem and progenitor cells are highlighted to demonstrate their migration, lineage commitment, and potential roles in wound healing.

AB - Directed movement of stem cells is crucial not only for organogenesis during development, but also for tissue regeneration in adult life. This chapter presents examples of stem cell migration and recruitment and the application of cell homing in orofacial regeneration. Cell homing refers to the recruitment of endogenous cells, including stem and progenitor cells, into a wound. Homing can be local and/or systemic. Whereas cell homing via circulation has contributed a great deal to the knowledge of pathogenesis of diverse diseases, including infections and tumor metastasis, we understand little of how to immobilize and direct cell homing in tissue regeneration. Stem and progenitor cells are highlighted to demonstrate their migration, lineage commitment, and potential roles in wound healing.

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Craniofacial Tissue Bioengineering and Regeneration by Endogenous Stem Cells

Abstract

Keywords

ASJC Scopus subject areas

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