Covalently cross-linked Watson-Crick base pair models. Part 2

Yao Ling Qiu, Hong Yu Li, George Topalov, Yoshito Kishi

Research output: Contribution to journalArticlepeer-review

12 Scopus citations


A concise and practical route has been developed for a synthesis of the CH2-bridged base pairs represented by the type-II structure. The structural studies suggest the possibility that these base pairs mimic the molecular architecture of Watson-Crick hydrogen-bonded base pairs.

Original languageEnglish (US)
Pages (from-to)9425-9429
Number of pages5
JournalTetrahedron Letters
Issue number49
StatePublished - Dec 2 2000
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry


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