Corilocal scanning laser evaluation of repeated Q-switched laser exposure and possible retinal NFL damage

H. Zwick, D. A. Gagliano, J. A. Zuclich, B. E. Stuck, D. J. Lund, R. Glickman

Research output: Contribution to journalConference articlepeer-review

1 Scopus citations


Repeated extended source Q-switched exposure centered on the macula has been shown to produce a Bullseye maculopathy°. This paper provides a confocal scanning laser ophthalmoscopic evaluation with regard to the retinal nerve fiber layer (NFL) and deeper choroidal vascular network. Confocal imaging revealed that the punctate annular appearance of this lesion in the deeper retinal layers is associated with retinal nerve fiber bundle disruptions and small gaps in the retinal NFL. No choroidal dysfunction was noticed with Indocyanine green angiography. It is hypothesized that retinal NFL damage occurs either through disruption of retinal pigment epithelial cell layer support to the NFL or through direct exposure to high spatial peak powers within the extended source beam profile, causing direct micro-thermal injury to the NFL The apparent sparring of the fovea reflects central retinal morphology rather than a lack of retinal damage to the fovea.

Original languageEnglish (US)
Pages (from-to)634-640
Number of pages7
JournalProceedings of SPIE - The International Society for Optical Engineering
StatePublished - May 22 1995
EventLaser-Tissue Interaction VI 1995 - San Jose, United States
Duration: Feb 1 1995Feb 8 1995

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering


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