Controversial cytogenetic observations in mammalian somatic cells exposed to extremely low frequency electromagnetic radiation: A review and future research recommendations

Vijayalaxmi, Guenter Obe

Research output: Contribution to journalReview article

74 Scopus citations

Abstract

During the years 1990-2003, a large number of investigations were conducted using animals, cultured rodent and human cells as well as freshly collected human blood lymphocytes to determine the genotoxic potential of exposure to nonionizing radiation emitted from extremely low frequency electromagnetic fields (EMF). Among the 63 peer reviewed scientific reports, the conclusions from 29 studies (46%) did not indicate increased damage to the genetic material, as assessed from DNA strand breaks, incidence of chromosomal aberrations (CA), micronuclei (MN). and sister chromatid exchanges (SCE), in EMF exposed cells as compared with sham exposed and/or unexposed cells, while those from 14 investigations (22%) have suggested an increase in such damage in EMF exposed cells. The observations from 20 other studies (32%) were inconclusive. This study reviews the investigations published in peer reviewed scientific journals during 1990-2003 and attempts to identify probable reason(s) for the conflicting results. Recommendations are made for future research to address some of the controversial observations.

Original languageEnglish (US)
Pages (from-to)412-430
Number of pages19
JournalBioelectromagnetics
Volume26
Issue number5
DOIs
StatePublished - Jul 2005

Keywords

  • Chromosomal aberrations
  • DNA strand breaks
  • ELF
  • Electric fields
  • Magnetic fields
  • Micronucleid
  • Sister chromatid exchanges

ASJC Scopus subject areas

  • Biophysics
  • Physiology
  • Radiology Nuclear Medicine and imaging

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