Controversial cytogenetic observations in mammalian somatic cells exposed to radiofrequency radiation

Vijayalaxmi, Guenter Obe

Research output: Contribution to journalReview articlepeer-review

110 Scopus citations

Abstract

During the years 1990-2003 a large number of investigations were conducted using rodents, cultured rodent and human cells, and freshly collected human blood lymphocytes to determine the genotoxic potential of exposure to radiofrequency (RF) radiation. The results of most of these studies (58%) did not indicate increased damage to the genetic material (assessed from DNA strand breaks, incidence of chromosomal aberrations, micronuclei and sister chromatid exchanges) in cells exposed to RF radiation compared to shamexposed and/or unexposed cells. Some investigations (23%) reported an increase in such damage in cells exposed to RF radiation. The observations from other studies (19%) were inconclusive. This paper reviews the investigations published in scientific journals during 1990-2003 and attempts to identify probable reason(s) for the conflicting results. Recommendations are made for future research to address some of the controversial observations.

Original languageEnglish (US)
Pages (from-to)481-496
Number of pages16
JournalRadiation Research
Volume162
Issue number5
DOIs
StatePublished - Nov 1 2004

ASJC Scopus subject areas

  • Biophysics
  • Radiation
  • Radiology Nuclear Medicine and imaging

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