Controlling bacterial fouling with polyurethane/ N -halamine semi-interpenetrating polymer networks

Kemao Xiu, Jianchuan Wen, Nuala Porteous, Yuyu Sun

Research output: Contribution to journalArticlepeer-review

12 Scopus citations


N-halamine-based interpenetrating polymer networks were developed as a simple and effective strategy in the preparation of antimicrobial polymers. An N-halamine monomer, N-chloro-2, 2, 6, 6-tetramethyl-4-piperidyl methacrylate, was incorporated into polyurethane in the presence of a cross-linker and an initiator. Post-polymerization of the monomers led to the formation of polyurethane/N-halamine semi-interpenetrating polymer networks. The presence of N-halamines in the semi-interpenetrating polymer networks was confirmed by attenuated total reflectance infrared, water contact angle, and energy-dispersive X-ray spectroscopy analysis. The N-halamine contents in the semi-interpenetrating polymer networks could be readily controlled by changing reaction conditions. The distribution of active chlorines within the semi-interpenetrating polymer networks was characterized with energy-dispersive X-ray spectroscopy. Contact mode antimicrobial tests, zone of inhibition studies, and scanning electron microscopy observations showed that the semi-interpenetrating polymer networks had potent antimicrobial and antifouling effects against both Gram-positive and Gram-negative bacteria. Release tests demonstrated the outstanding stability of the N-halamine structures in the new semi-interpenetrating polymer networks.

Original languageEnglish (US)
Pages (from-to)542-554
Number of pages13
JournalJournal of Bioactive and Compatible Polymers
Issue number5
StatePublished - Sep 1 2017


  • Interpenetrating polymer network
  • N -halamine
  • antimicrobial
  • fouling
  • polyurethane

ASJC Scopus subject areas

  • Bioengineering
  • Biomaterials
  • Polymers and Plastics
  • Materials Chemistry


Dive into the research topics of 'Controlling bacterial fouling with polyurethane/ N -halamine semi-interpenetrating polymer networks'. Together they form a unique fingerprint.

Cite this