Continuous light paradoxically reduces catecholamine-induced melatonin production

William E. Heydorn, Irwin Lucki, Alan Frazer

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Exposure of rats to continuous light for 14 days reduced the stimulation of melatonin content in the pineal gland produced by either isoproterenol administration or exposure to darkness. Since continuous light has been reported to enhance many intermediate biochemical events leading to the synthesis of melatonin, these results demonstrate the importance of examining the end-product of an organ when evaluating the physiological significance of biochemical changes in model biological systems.

Original languageEnglish (US)
Pages (from-to)175-178
Number of pages4
JournalBrain Research
Issue number1
StatePublished - May 9 1983
Externally publishedYes


  • beta-receptors
  • continuous light
  • isoproterenol
  • norepinephrine
  • pineal gland

ASJC Scopus subject areas

  • Clinical Neurology
  • Molecular Biology
  • General Neuroscience
  • Developmental Biology


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