Contingency management and cognitive behavior therapy for smoking cessation among veterans with posttraumatic stress disorder: Design and methodology of a randomized clinical trial

Stephanie Y. Wells, Stefanie T. LoSavio, Tapan A. Patel, Mariah K. Evans, Jean C. Beckham, Patrick Calhoun, Eric A. Dedert

Research output: Contribution to journalArticlepeer-review

Abstract

Background: Smoking is a prevalent concern among Veterans, especially those with posttraumatic stress disorder (PTSD). Despite the availability of interventions for smoking cessation, these treatments have not been as effective among Veteran populations, particularly Veterans with PTSD. The present study seeks to describe the methods of a randomized clinical trial examining the efficacy of CPT-SMART, a multidimensional treatment combining cognitive processing therapy (CPT) for PTSD, smoking cessation counseling, pharmacotherapy, and contingency management (CM) compared to a yoked comparison group. Methods: One hundred twenty Veterans with PTSD who smoke cigarettes will be enrolled. All participants will receive CPT in addition to counseling and pharmacotherapy for smoking cessation. Participants will be randomized to the CPT-SMART condition, which includes monetary reinforcement that is contingent on bioverification of smoking abstinence (i.e., contingency management), or a yoked comparison with monetary reinforcement matched to the participant to whom they are yoked. The primary outcome is bioverified smoking abstinence at the 6-month follow-up appointment. Conclusion: If shown efficacious, a combined PTSD and smoking treatment plus incentive-based approach for smoking could be implemented into specialty PTSD programs. The positive public health impact of reducing smoking among Veterans with PTSD could be enormous as it would prevent significant smoking-related morbidity and mortality.

Original languageEnglish (US)
Article number106839
JournalContemporary Clinical Trials
Volume119
DOIs
StatePublished - Aug 2022
Externally publishedYes

Keywords

  • Cognitive processing therapy
  • Contingency management
  • PTSD
  • Smoking
  • Smoking cessation

ASJC Scopus subject areas

  • Pharmacology (medical)

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