Consensus paper: Roles of the cerebellum in motor control-the diversity of ideas on cerebellar involvement in movement

Mario Manto, James M. Bower, Adriana Bastos Conforto, José M. Delgado-García, Suzete Nascimento Farias Da Guarda, Marcus Gerwig, Christophe Habas, Nobuhiro Hagura, Richard B. Ivry, Peter Marien, Marco Molinari, Eiichi Naito, Dennis A. Nowak, Nordeyn Oulad Ben Taib, Denis Pelisson, Claudia D. Tesche, Caroline Tilikete, Dagmar Timmann

Research output: Contribution to journalArticle

299 Scopus citations

Abstract

Considerable progress has been made in developing models of cerebellar function in sensorimotor control, as well as in identifying key problems that are the focus of current investigation. In this consensus paper, we discuss the literature on the role of the cerebellar circuitry in motor control, bringing together a range of different viewpoints. The following topics are covered: oculomotor control, classical conditioning (evidence in animals and in humans), cerebellar control of motor speech, control of grip forces, control of voluntary limb movements, timing, sensorimotor synchronization, control of corticomotor excitability, control of movement-related sensory data acquisition, cerebro-cerebellar interaction in visuokinesthetic perception of hand movement, functional neuroimaging studies, and magnetoencephalographic mapping of cortico-cerebellar dynamics. While the field has yet to reach a consensus on the precise role played by the cerebellum in movement control, the literature has witnessed the emergence of broad proposals that address cerebellar function at multiple levels of analysis. This paper highlights the diversity of current opinion, providing a framework for debate and discussion on the role of this quintessential vertebrate structure.

Original languageEnglish (US)
Pages (from-to)457-487
Number of pages31
JournalCerebellum
Volume11
Issue number2
DOIs
StatePublished - Jun 1 2012

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Keywords

  • Cerebellum
  • Classical conditioning
  • Cortex
  • Dysmetria
  • Excitability
  • Eye movements
  • FMRI
  • Grasping
  • Grip force
  • Magnetoencephalography (MEG)
  • Motor speech
  • Network
  • Nuclei
  • Predictive
  • Purkinje neurons
  • Sensory
  • Stability
  • Synchronization
  • Timing
  • Torques

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

Cite this

Manto, M., Bower, J. M., Conforto, A. B., Delgado-García, J. M., Da Guarda, S. N. F., Gerwig, M., Habas, C., Hagura, N., Ivry, R. B., Marien, P., Molinari, M., Naito, E., Nowak, D. A., Ben Taib, N. O., Pelisson, D., Tesche, C. D., Tilikete, C., & Timmann, D. (2012). Consensus paper: Roles of the cerebellum in motor control-the diversity of ideas on cerebellar involvement in movement. Cerebellum, 11(2), 457-487. https://doi.org/10.1007/s12311-011-0331-9