Abstract
Gas chromatography-mass spectrometry was used to identify a dopamine metabolite isolated from the substantia nigra of parkinsonian brain tissue. Incubation of dopamine with monoamine oxidase B gave the same product which was identified as 3,4-dihydroxyphenylacetaldehyde. The structure of the compound was established by chemical synthesis, metastable ion measurement and high-resolution mass spectrometry.
Original language | English (US) |
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Pages (from-to) | 205-212 |
Number of pages | 8 |
Journal | Journal of Chromatography B: Biomedical Sciences and Applications |
Volume | 614 |
Issue number | 2 |
DOIs | |
State | Published - May 5 1993 |
Externally published | Yes |
ASJC Scopus subject areas
- General Chemistry