Concordance and discriminatory power of cough measurement devices for individuals with parkinson disease

Erin P. Silverman, Giselle Carnaby-Mann, Teresa Pitts, Paul Davenport, Michael S. Okun, Christine Sapienza

Research output: Contribution to journalArticlepeer-review

14 Scopus citations

Abstract

Background: Dysphagia and aspiration pneumonia are two causes of morbidity in Parkinson disease (PD). In PD, impaired airway clearance can lead to penetration of foreign material, resulting in a high prevalence of aspiration pneumonia and death. This study examines three different devices for measurement of peak airfl ow during voluntary cough in healthy control subjects and those with PD. Two simple and low-cost devices for measuring peak cough airfl ow were compared with the "gold standard" pneumotachograph. Methods: Thirty-fi ve healthy control subjects and 35 individuals with PD produced voluntary cough at three perceived strengths (weak, moderate, and strong cough) for each of the three devices. Results: A signifi cant difference in mean peak cough airfl ow was demonstrated for disease ( F [1,56] = 4.0, P < .05) and sex ( F [1,56] = 9.59, P < .003) across devices. The digital and analog meters were comparable to the gold standard demonstrating no signifi cant difference (statistical) by device (digital vs analog) in receiver operating characteristic curve analysis. Both devices were discriminative of the presence of PD. Conclusions: The analog and digital peak airfl ow meters are suitable alternatives to the gold standard pneumotachograph due to their low cost, portability, ease of use, and high sensitivity relative to normative peak cough airfl ows. Voluntary cough airfl ow measures may serve as a noninvasive means of screening for aspiration risk in target populations. Additionally, quantifi cation of cough strength through use of predetermined limens for weak, moderate, and strong cough may assist clinicians in better describing and tracking cough strength as a contributing factor to aspiration risk.

Original languageEnglish (US)
Pages (from-to)1089-1096
Number of pages8
JournalChest
Volume145
Issue number5
DOIs
StatePublished - May 2014
Externally publishedYes

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Critical Care and Intensive Care Medicine
  • Cardiology and Cardiovascular Medicine

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