Concomitant Presentation of Adermatopathic Dermatomyositis, Statin Myopathy, Fibromyalgia Syndrome, Piriformis Muscle Myofascial Pain Syndrome, and Diabetic Neuropathy

Brent Wagner, Kathleen S. Kagan-Hallet, I. Jon Russell

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

Background: Differentiation of dermatomyositis from other myopathic conditions depends on characteristic histolopathologic findings on muscle biopsy. A 48-year-old diabetic man had a prior history of generalized myalgia and an elevated serum creatine kinase while on a statin. Within a few months after discontinuation of the statin, the myalgia symptoms improved and the creatine kinase normalized. Findings: An incisional biopsy of the gastrocnemius muscle revealed perifascicular muscle fiber damage, microvascular inflammation, pyknotic cytoplasmic inclusion bodies, and neurogenic atrophy with reinnervation consistent with diabetic neuropathy. Conclusion: We present the clinical findings from a patient with adermatopathic dermatomyositis in the setting of diabetic neuropathy, fibromyalgia syndrome, piriformis syndrome, and 3-hydroxy-3-methyl-glutaryl-coenzyme A [HMG-CoA] reductase inhibitor myopathy.

Original languageEnglish (US)
Pages (from-to)25-30
Number of pages6
JournalJournal of Musculoskeletal Pain
Volume11
Issue number2
DOIs
StatePublished - Nov 17 2003

Keywords

  • Dermatomyositis
  • Diabetic neuropathy
  • HMG-CoA reductase inhibitors
  • Muscle weakness
  • Muscular diseases
  • Muscular weakness

ASJC Scopus subject areas

  • Rheumatology

Fingerprint Dive into the research topics of 'Concomitant Presentation of Adermatopathic Dermatomyositis, Statin Myopathy, Fibromyalgia Syndrome, Piriformis Muscle Myofascial Pain Syndrome, and Diabetic Neuropathy'. Together they form a unique fingerprint.

Cite this