Computer simulation of a living cell: Part I

R. Weinberg, M. Berkus

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Abstract

This paper, to be presented in two parts, is concerned with the problem of a realistic and useful simulation of a living cell, the simple unicellular bacterium Escherichia coli, the program being written in Fortran IV for an IBM 360/67 computer. The object is to represent the cell in such a way as to simulate its growth in real environments of a living cell, as well as during changes from one chemical environment to another. This simulation could also supply useful information for answering current questions in biology. In Part 1 the authors consider the criteria for the success of the simulation, its reality and potential usefulness, and describe the method of simulation, as well as that of allosteric inhibition.

Original languageEnglish (US)
Pages (from-to)95-120
Number of pages26
JournalInternational Journal of Bio-Medical Computing
Volume2
Issue number2
DOIs
StatePublished - Apr 1971

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ASJC Scopus subject areas

  • Medicine (miscellaneous)

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