@inproceedings{34aff3bef9964c798ec9ea68cd56825a,
title = "Comprehensive investigation of connectivity map data-towards a drug mode of action network for personalized thnerapy",
abstract = "This work aims at addressing the problems existed in the original cMap algorithm and proposed a new drug Mode-of Action Network construction scheme including data pre-processing, signature gene extraction, network construction and query prediction. Multiple analyses were conducted to investigate the structure of constructed drug mode-of-action network and the cMap based Mode-of-Action network is tested on the independent drug treatment datasets. All result shows our cMap based drug Mode-of-Action network is both statistically and biologically significant and out-perform the original cMap project.",
keywords = "Drug Mode of Action, Network and Prediction",
author = "Chifeng Ma and Yufei Huang and Harry, {Huang I.} and Yidong Chen",
year = "2011",
doi = "10.1109/BIBMW.2011.6112555",
language = "English (US)",
isbn = "9781457716133",
series = "2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2011",
pages = "1045--1047",
booktitle = "2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2011",
note = "2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2011 ; Conference date: 12-11-2011 Through 15-11-2011",
}