Complications of Diabetes Therapy

Sarah D. Corathers; Shawn Peavie; Marzieh Salehi

doi:10.1016/j.ecl.2013.06.005

Complications of Diabetes Therapy

Sarah D. Corathers, Shawn Peavie, Marzieh Salehi

Research output: Contribution to journal › Review article › peer-review

23 Scopus citations

Abstract

Current strategies for the treatment of type 2 diabetes mellitus promote individualized plans to achieve target glucose levels on a patient-by-patient basis while minimizing treatment related risks. Maintaining glycemic control over time is a significant challenge because of the progressive nature of diabetes as a result of declining β-cell function. This article identifies complications of non-insulin treatments for diabetes. The major classes of medications are reviewed with special focus on target population, mechanism of action, effect on weight, cardiovascular outcomes and additional class-specific side effects including effects on bone. Effects on β-cell function are also highlighted.

Original language	English (US)
Pages (from-to)	947-970
Number of pages	24
Journal	Endocrinology and Metabolism Clinics of North America
Volume	42
Issue number	4
DOIs	https://doi.org/10.1016/j.ecl.2013.06.005
State	Published - Dec 2013
Externally published	Yes

Keywords

Cardiovascular outcomes
Diabetes
Treatment complications
β-cell function

ASJC Scopus subject areas

Endocrinology
Endocrinology, Diabetes and Metabolism

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10.1016/j.ecl.2013.06.005

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title = "Complications of Diabetes Therapy",

abstract = "Current strategies for the treatment of type 2 diabetes mellitus promote individualized plans to achieve target glucose levels on a patient-by-patient basis while minimizing treatment related risks. Maintaining glycemic control over time is a significant challenge because of the progressive nature of diabetes as a result of declining β-cell function. This article identifies complications of non-insulin treatments for diabetes. The major classes of medications are reviewed with special focus on target population, mechanism of action, effect on weight, cardiovascular outcomes and additional class-specific side effects including effects on bone. Effects on β-cell function are also highlighted.",

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AU - Peavie, Shawn

AU - Salehi, Marzieh

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AB - Current strategies for the treatment of type 2 diabetes mellitus promote individualized plans to achieve target glucose levels on a patient-by-patient basis while minimizing treatment related risks. Maintaining glycemic control over time is a significant challenge because of the progressive nature of diabetes as a result of declining β-cell function. This article identifies complications of non-insulin treatments for diabetes. The major classes of medications are reviewed with special focus on target population, mechanism of action, effect on weight, cardiovascular outcomes and additional class-specific side effects including effects on bone. Effects on β-cell function are also highlighted.

KW - Cardiovascular outcomes

KW - Diabetes

KW - Treatment complications

KW - β-cell function

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Complications of Diabetes Therapy

Abstract

Keywords

ASJC Scopus subject areas

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