Complications of Diabetes Therapy

Sarah D. Corathers, Shawn Peavie, Marzieh Salehi

Research output: Contribution to journalReview article

11 Citations (Scopus)

Abstract

Current strategies for the treatment of type 2 diabetes mellitus promote individualized plans to achieve target glucose levels on a patient-by-patient basis while minimizing treatment related risks. Maintaining glycemic control over time is a significant challenge because of the progressive nature of diabetes as a result of declining β-cell function. This article identifies complications of non-insulin treatments for diabetes. The major classes of medications are reviewed with special focus on target population, mechanism of action, effect on weight, cardiovascular outcomes and additional class-specific side effects including effects on bone. Effects on β-cell function are also highlighted.

Original languageEnglish (US)
Pages (from-to)947-970
Number of pages24
JournalEndocrinology and Metabolism Clinics of North America
Volume42
Issue number4
DOIs
StatePublished - Dec 1 2013
Externally publishedYes

Fingerprint

Diabetes Complications
Health Services Needs and Demand
Type 2 Diabetes Mellitus
Therapeutics
Weights and Measures
Bone and Bones
Glucose

Keywords

  • β-cell function
  • Cardiovascular outcomes
  • Diabetes
  • Treatment complications

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

Cite this

Complications of Diabetes Therapy. / Corathers, Sarah D.; Peavie, Shawn; Salehi, Marzieh.

In: Endocrinology and Metabolism Clinics of North America, Vol. 42, No. 4, 01.12.2013, p. 947-970.

Research output: Contribution to journalReview article

Corathers, Sarah D. ; Peavie, Shawn ; Salehi, Marzieh. / Complications of Diabetes Therapy. In: Endocrinology and Metabolism Clinics of North America. 2013 ; Vol. 42, No. 4. pp. 947-970.
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