Comparison of the diagnostic value of bone marrow biopsy and bone marrow aspiration in neoplastic disease

J. D. Bearden, G. A. Ratkin, C. A. Coltman

Research output: Contribution to journalArticlepeer-review

38 Scopus citations

Abstract

The Jamshidi Swaim biopsy needle was utilized to perform 205 bone marrow biopsies, accompanied by simultaneous bone marrow aspirates, on patients with lymphoma, leukemia, and a variety of solid tumors. There was no significant morbidity. There were 67 positive findings with biopsy and 42 with aspiration. The 2 techniques were complementary in Hodgkin's disease, non Hodgkin's lymphoma, breast carcinoma, bronchogenic carcinoma, malignant melanoma, and in leukemia. The bone marrow biopsies and aspirates were examined with respect to the adequacy of the bone marrow biopsy specimen, the number of positive biopsies in the various categories of neoplasia, and the disparity of biopsy and aspirate. 28 of the 67 positive biopsies (41.8%) had negative aspirates. These data and specimens obtained compared quite favorably with other series in which a modification of the Vim Silverman needle was used.

Original languageEnglish (US)
Pages (from-to)738-740
Number of pages3
JournalJournal of Clinical Pathology
Volume27
Issue number9
DOIs
StatePublished - 1974
Externally publishedYes

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

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