Comparison of single-fiber and macro electrode recordings: Relationship to motor unit action potential duration

Daniel Dumitru, John C. King, Sanjeev D. Nandedkar

Research output: Contribution to journalArticle

11 Scopus citations

Abstract

The factors contributing to the duration of a motor unit action potential (MUAP) are believed to be well known, with both manual measurements and computer simulations agreeing with respect to MUAP durations approaching 10 ms. In this investigation, it is clearly demonstrated that use of a wide- open amplifier bandpass combined with signal-to-noise ratio enhancement results in MUAP durations approaching 30 ms recorded with either a macro or single-fiber electrode. Why the clinically recorded MUAP duration differs significantly from these physiologic durations is discussed. A hypothesis is presented whereby the major contributing factor toward MUAP duration is the total time of action potential transmembrane current flow along the muscle fiber from end-plate zone to musculotendinous junction.

Original languageEnglish (US)
Pages (from-to)1381-1388
Number of pages8
JournalMuscle and Nerve
Volume20
Issue number11
DOIs
StatePublished - Oct 28 1997

Keywords

  • Macroelectromyography
  • Motor unit action potential
  • Muscle action potential
  • Muscle fiber duration
  • Single-fiber electromyography

ASJC Scopus subject areas

  • Physiology
  • Clinical Neurology
  • Cellular and Molecular Neuroscience
  • Physiology (medical)

Fingerprint Dive into the research topics of 'Comparison of single-fiber and macro electrode recordings: Relationship to motor unit action potential duration'. Together they form a unique fingerprint.

  • Cite this