Comparison of quantitation of left ventricular volume, ejection fraction, and cardiac output in patients with atrial fibrillation by cine magnetic resonance imaging versus invasive measurements

W. Gregory Hundley, Benjamin M. Meshack, Du Wayne L. Willett, Dany E. Sayad, Richard A. Lange, John E. Willard, Charles Landau, L. David Hillis, Ronald M. Peshock

Research output: Contribution to journalArticlepeer-review

35 Scopus citations

Abstract

Currently available invasive and noninvasive techniques for the determination of left ventricular end-diastolic and end-systolic volumes, ejection fraction, and cardiac output are more time-consuming and potentially less accurate in patients with atrial fibrillation (AF) than in those with sinus rhythm. Although magnetic resonance imaging (MRI) can rapidly and accurately measure these variables in patients with sinus rhythm, its ability to do so in subjects with AF is not known. To determine if left ventricular volumes, ejection fraction, and cardiac output can be measured accurately in patients with AF using MRI, 26 subjects (13 women and 13 men, aged 15 to 76 years) in sinus rhythm (n = 13) or AF (n = 13) underwent MRI followed immediately by invasive measurements of these indexes. For those in AF, MRI measurements of left ventricular end-diastolic volume, end-systolic volume, stroke volume, ejection fraction, and cardiac output correlated well with catheterization measurements (r = 0.90, 0.90, 0.95, 0.85, and 0.90, respectively). In addition, the mean difference between MRI and catheterization measurements was similar in subjects with AF and in those with sinus rhythm. Compared with standard invasive measurements, MRI provides an accurate noninvasive determination of left ventricular volumes, ejection fraction, and cardiac output in patients with AF.

Original languageEnglish (US)
Pages (from-to)1119-1123
Number of pages5
JournalAmerican Journal of Cardiology
Volume78
Issue number10
DOIs
StatePublished - 1996

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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