Comparison of operative risks associated with radical hysterectomy in pregnant and nonpregnant women

Charles A. Leath, Kerri S. Bevis, T. Michael Numnum, Patrick S. Ramsey, Warner K. Huh, J. Michael Straughn

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

OBJECTIVE: To compare the operative data and complications of radical hysterectomy performed on pregnant women versus nonpregnant women. STUDY DESIGN: Following institutional review board approval, we reviewed our surgical databases to identify pregnant women who had undergone a radical hysterectomy for cervical carcinoma from 1992-2005 (n=7). A non-pregnant control group (n=35) of women undergoing radical hysterectomy during the study interval were identified and matched for age, year of surgery, and surgeon. Pertinent operative and outcome data were abstracted and compared RESULTS: Of the 7 women who had undergone a radical hysterectomy during pregnancy, 4 had a cesarean radical hysterectomy at a mean gestational age of 35.4 weeks (range, 32.3-38 weeks) and 3 had a radical hysterectomy with a previable fetus in situ at a mean gestational age of 14.2 weeks. Demographics were similar between groups. Transfusion rates were significantly higher among pregnant women (57%) as compared to non-pregnant controls (9%) (p =0.0009). The overall incidence of operative complications was similar between the pregnant women (43%) and nonpregnant controls (40%) (p = NS). CONCLUSION: Radical hysterectomy performed in pregnant women was associated with higher blood loss and increased need for transfusion as compared to non-pregnant controls. No differences were observed in regards to other operative surgical complications between the two groups.

Original languageEnglish (US)
Pages (from-to)279-284
Number of pages6
JournalJournal of Reproductive Medicine
Volume58
Issue number7-8
StatePublished - Aug 2013
Externally publishedYes

Keywords

  • Cervical cancer
  • Gynecologic surgery
  • Hysterectomy
  • Operative morbidity
  • Pregnancy

ASJC Scopus subject areas

  • Reproductive Medicine
  • Obstetrics and Gynecology

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    Leath, C. A., Bevis, K. S., Numnum, T. M., Ramsey, P. S., Huh, W. K., & Straughn, J. M. (2013). Comparison of operative risks associated with radical hysterectomy in pregnant and nonpregnant women. Journal of Reproductive Medicine, 58(7-8), 279-284.