Comparison of in vitro activities of voriconazole and five established antifungal agents against different species of dermatophytes using a broth macrodilution method

S. Perea, A. W. Fothergill, D. A. Sutton, M. G. Rinaldi

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Abstract

The in vitro activities of voriconazole against 19 different species of dermatophytes were compared with those of terbinafine, itraconazole, ketoconazole, griseofulvin, and fluconazole. MICs were determined according to a National Committee for Clinical Laboratory Standards broth macrodilution method. Voriconazole appeared more active than ketoconazole, griseofulvin, and fluconazole and less active than itraconazole and terbinafine. Based on these results, voriconazole merits further investigation as a potentially useful agent for the treatment of dermatophytosis.

Original languageEnglish (US)
Pages (from-to)385-388
Number of pages4
JournalJournal of clinical microbiology
Volume39
Issue number1
DOIs
StatePublished - Jan 30 2001

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ASJC Scopus subject areas

  • Microbiology (medical)

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