Comparison of colon cleansing methods in preparation for colonoscopy

J. A. DiPalma, Charles E Brady Iii, D. L. Stewart

Research output: Contribution to journalArticle

154 Citations (Scopus)

Abstract

Colonoscopy cleansing regimens were evaluated in 197 patients randomized in two study phases to one of four methods: group 1 (64 patients), 3-day clear liquid diet; group 2 (40 patients), 3-day minimum-residue diet; group 3 (44 patients), 1-day minimum-residue diet; group 4 (49 patients), Golytely. Groups 1-3 also received laxatives and enemas before colonoscopy. Physician assessment by endoscopists unaware of the method of colon cleansing favored group 4 (p < 0.001), with good to excellent preparations achieved in 69% of group 1, 80% of groups 2 and 3, and 92% of group 4. Group 4 patients also experienced less abdominal distress (p < 0.01). Breath hydrogen and methane levels were measured in groups 3 and 4 both before and after preparation. The decrease in pre- to postprep levels of hydrogen and methane were not significantly different between the groups and postprep gas concentrations were below combustible levels in both groups. There were no clinically significant differences between the four groups for any of the other measured hematologic or biochemical parameters. It is concluded that Golytely is a safe, effective method of colon cleansing, well tolerated by patients.

Original languageEnglish (US)
Pages (from-to)856-860
Number of pages5
JournalGastroenterology
Volume86
Issue number5 I
StatePublished - 1984
Externally publishedYes

Fingerprint

Colonoscopy
Colon
Methane
Diet
Hydrogen
Laxatives
Enema
Gases
Physicians

ASJC Scopus subject areas

  • Gastroenterology

Cite this

DiPalma, J. A., Brady Iii, C. E., & Stewart, D. L. (1984). Comparison of colon cleansing methods in preparation for colonoscopy. Gastroenterology, 86(5 I), 856-860.

Comparison of colon cleansing methods in preparation for colonoscopy. / DiPalma, J. A.; Brady Iii, Charles E; Stewart, D. L.

In: Gastroenterology, Vol. 86, No. 5 I, 1984, p. 856-860.

Research output: Contribution to journalArticle

DiPalma, JA, Brady Iii, CE & Stewart, DL 1984, 'Comparison of colon cleansing methods in preparation for colonoscopy', Gastroenterology, vol. 86, no. 5 I, pp. 856-860.
DiPalma JA, Brady Iii CE, Stewart DL. Comparison of colon cleansing methods in preparation for colonoscopy. Gastroenterology. 1984;86(5 I):856-860.
DiPalma, J. A. ; Brady Iii, Charles E ; Stewart, D. L. / Comparison of colon cleansing methods in preparation for colonoscopy. In: Gastroenterology. 1984 ; Vol. 86, No. 5 I. pp. 856-860.
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