Comparison of antifungal susceptibilities to fluconazole and voriconazole of oral Candida glabrata isolates from head and neck radiation patients

A. K. Burn, A. W. Fothergill, W. R. Kirkpatrick, B. J. Coco, T. F. Patterson, D. I. McCarthy, M. G. Rinaldi, S. W. Redding

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The antifungal susceptibilities of 79 oral Candida glabrata isolates to fluconazole and voriconazole were compared. The MICs at which 90% of the isolates tested were inhibited were 1 μg of voriconazole/ml and 32 μg of fluconazole/ml. Oral C. glabrata isolates for which the fluconazole MICs are elevated are commonly those for which the voriconazole MICs are elevated, but these increases may be transient for voriconazole, as they are for fluconazole.

Original languageEnglish (US)
Pages (from-to)5846-5848
Number of pages3
JournalJournal of clinical microbiology
Issue number12
Publication statusPublished - Dec 1 2004


ASJC Scopus subject areas

  • Microbiology (medical)

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