Comparison of antifungal susceptibilities to fluconazole and voriconazole of oral Candida glabrata isolates from head and neck radiation patients

A. K. Burn; A. W. Fothergill; W. R. Kirkpatrick; B. J. Coco; T. F. Patterson; D. I. McCarthy; M. G. Rinaldi; S. W. Redding

doi:10.1128/JCM.42.12.5846-5848.2004

Comparison of antifungal susceptibilities to fluconazole and voriconazole of oral Candida glabrata isolates from head and neck radiation patients

A. K. Burn, A. W. Fothergill, W. R. Kirkpatrick, B. J. Coco, T. F. Patterson, D. I. McCarthy, M. G. Rinaldi, S. W. Redding

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

The antifungal susceptibilities of 79 oral Candida glabrata isolates to fluconazole and voriconazole were compared. The MICs at which 90% of the isolates tested were inhibited were 1 μg of voriconazole/ml and 32 μg of fluconazole/ml. Oral C. glabrata isolates for which the fluconazole MICs are elevated are commonly those for which the voriconazole MICs are elevated, but these increases may be transient for voriconazole, as they are for fluconazole.

Original language	English (US)
Pages (from-to)	5846-5848
Number of pages	3
Journal	Journal of clinical microbiology
Volume	42
Issue number	12
DOIs	https://doi.org/10.1128/JCM.42.12.5846-5848.2004
State	Published - Dec 2004

ASJC Scopus subject areas

Microbiology (medical)

Access to Document

10.1128/JCM.42.12.5846-5848.2004

Cite this

Burn, A. K., Fothergill, A. W., Kirkpatrick, W. R., Coco, B. J., Patterson, T. F., McCarthy, D. I., Rinaldi, M. G., & Redding, S. W. (2004). Comparison of antifungal susceptibilities to fluconazole and voriconazole of oral Candida glabrata isolates from head and neck radiation patients. Journal of clinical microbiology, 42(12), 5846-5848. https://doi.org/10.1128/JCM.42.12.5846-5848.2004

Burn, AK, Fothergill, AW, Kirkpatrick, WR, Coco, BJ, Patterson, TF, McCarthy, DI, Rinaldi, MG & Redding, SW 2004, 'Comparison of antifungal susceptibilities to fluconazole and voriconazole of oral Candida glabrata isolates from head and neck radiation patients', Journal of clinical microbiology, vol. 42, no. 12, pp. 5846-5848. https://doi.org/10.1128/JCM.42.12.5846-5848.2004

@article{aa034b7cf7b7472ea8d21fb94a546b76,

title = "Comparison of antifungal susceptibilities to fluconazole and voriconazole of oral Candida glabrata isolates from head and neck radiation patients",

abstract = "The antifungal susceptibilities of 79 oral Candida glabrata isolates to fluconazole and voriconazole were compared. The MICs at which 90% of the isolates tested were inhibited were 1 μg of voriconazole/ml and 32 μg of fluconazole/ml. Oral C. glabrata isolates for which the fluconazole MICs are elevated are commonly those for which the voriconazole MICs are elevated, but these increases may be transient for voriconazole, as they are for fluconazole.",

author = "Burn, {A. K.} and Fothergill, {A. W.} and Kirkpatrick, {W. R.} and Coco, {B. J.} and Patterson, {T. F.} and McCarthy, {D. I.} and Rinaldi, {M. G.} and Redding, {S. W.}",

year = "2004",

month = dec,

doi = "10.1128/JCM.42.12.5846-5848.2004",

language = "English (US)",

volume = "42",

pages = "5846--5848",

journal = "Journal of clinical microbiology",

issn = "0095-1137",

publisher = "American Society for Microbiology",

number = "12",

}

TY - JOUR

T1 - Comparison of antifungal susceptibilities to fluconazole and voriconazole of oral Candida glabrata isolates from head and neck radiation patients

AU - Burn, A. K.

AU - Fothergill, A. W.

AU - Kirkpatrick, W. R.

AU - Coco, B. J.

AU - Patterson, T. F.

AU - McCarthy, D. I.

AU - Rinaldi, M. G.

AU - Redding, S. W.

PY - 2004/12

Y1 - 2004/12

N2 - The antifungal susceptibilities of 79 oral Candida glabrata isolates to fluconazole and voriconazole were compared. The MICs at which 90% of the isolates tested were inhibited were 1 μg of voriconazole/ml and 32 μg of fluconazole/ml. Oral C. glabrata isolates for which the fluconazole MICs are elevated are commonly those for which the voriconazole MICs are elevated, but these increases may be transient for voriconazole, as they are for fluconazole.

AB - The antifungal susceptibilities of 79 oral Candida glabrata isolates to fluconazole and voriconazole were compared. The MICs at which 90% of the isolates tested were inhibited were 1 μg of voriconazole/ml and 32 μg of fluconazole/ml. Oral C. glabrata isolates for which the fluconazole MICs are elevated are commonly those for which the voriconazole MICs are elevated, but these increases may be transient for voriconazole, as they are for fluconazole.

UR - http://www.scopus.com/inward/record.url?scp=10844265209&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=10844265209&partnerID=8YFLogxK

U2 - 10.1128/JCM.42.12.5846-5848.2004

DO - 10.1128/JCM.42.12.5846-5848.2004

M3 - Article

C2 - 15583322

AN - SCOPUS:10844265209

SN - 0095-1137

VL - 42

SP - 5846

EP - 5848

JO - Journal of clinical microbiology

JF - Journal of clinical microbiology

IS - 12

ER -

Comparison of antifungal susceptibilities to fluconazole and voriconazole of oral Candida glabrata isolates from head and neck radiation patients

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this