TY - JOUR
T1 - Comparative value of 99mTc-sestamibi scintimammography and sonography in the diagnostic workup of breast masses
AU - Klaus, Anita J.
AU - Klingensmith, William C.
AU - Parker, Steve H.
AU - Stavros, A. Thomas
AU - Sutherland, Jerome D.
AU - Aldrete, Kathy D.
PY - 2000/6
Y1 - 2000/6
N2 - OBJECTIVE. This study was conducted to assess the relative roles of 99mTc-sestamibi scintimammography and sonography in the evaluation of breast lesions that are indeterminate or suspicious on mammography or clinical examination. SUBJECTS AND METHODS. Twenty-five patients with 33 biopsy-proven breast lesions underwent both scintimamography and sonography. Lesions were categorized as benign or requiting biopsy on the basis of the absence or presence of a focus of increased activity on scintimammography and the shape, orientation, and echogenicity of the lesion on sonography. RESULTS. Sensitivity and specificity in detecting breast cancer were 92% and 95%, respectively, for scintimammography and 100% and 48%, respectively, for sonography. The higher specificity of scintimammography was statistically significant (p<0.01). CONCLUSION. Although the overall accuracy of 99mTc- sestamibi scintimammography in the diagnosis of breast cancer was high, it has several disadvantages in comparison with sonography Scintimammography has a slightly higher false-negative rate for breast cancer, is unable to reveal cysts, is more expensive, takes longer to perform, and involves ionizing radiation. For these reasons, scintimammography with 99mTc-sestamibi is unlikely to either replace sonography or be frequently used in addition to sonography.
AB - OBJECTIVE. This study was conducted to assess the relative roles of 99mTc-sestamibi scintimammography and sonography in the evaluation of breast lesions that are indeterminate or suspicious on mammography or clinical examination. SUBJECTS AND METHODS. Twenty-five patients with 33 biopsy-proven breast lesions underwent both scintimamography and sonography. Lesions were categorized as benign or requiting biopsy on the basis of the absence or presence of a focus of increased activity on scintimammography and the shape, orientation, and echogenicity of the lesion on sonography. RESULTS. Sensitivity and specificity in detecting breast cancer were 92% and 95%, respectively, for scintimammography and 100% and 48%, respectively, for sonography. The higher specificity of scintimammography was statistically significant (p<0.01). CONCLUSION. Although the overall accuracy of 99mTc- sestamibi scintimammography in the diagnosis of breast cancer was high, it has several disadvantages in comparison with sonography Scintimammography has a slightly higher false-negative rate for breast cancer, is unable to reveal cysts, is more expensive, takes longer to perform, and involves ionizing radiation. For these reasons, scintimammography with 99mTc-sestamibi is unlikely to either replace sonography or be frequently used in addition to sonography.
UR - http://www.scopus.com/inward/record.url?scp=0034081152&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0034081152&partnerID=8YFLogxK
U2 - 10.2214/ajr.174.6.1741779
DO - 10.2214/ajr.174.6.1741779
M3 - Article
C2 - 10845522
AN - SCOPUS:0034081152
VL - 174
SP - 1779
EP - 1783
JO - AJR. American journal of roentgenology
JF - AJR. American journal of roentgenology
SN - 0361-803X
IS - 6
ER -