Comparative sequence analysis of tmRNA

Christian Zwieb; Iwona Wower; Jacek Wower

doi:10.1093/nar/27.10.2063

Comparative sequence analysis of tmRNA

Christian Zwieb, Iwona Wower, Jacek Wower

Research output: Contribution to journal › Review article › peer-review

75 Scopus citations

Abstract

Minimal secondary structures of the bacterial and plastid tmRNAs were derived by comparative analyses of 50 aligned tmRNA sequences. The structures include 12 helices and four pseudoknots and are refinements of earlier versions, but include only those base pairs for which there is comparative evidence. Described are the conserved and variable features of the tmRNAs from a wide phylogenetic spectrum, the structural properties specific to the bacterial subgroups and preliminary 3-dimensional models from the pseudo-knotted regions.

Original language	English (US)
Pages (from-to)	2063-2071
Number of pages	9
Journal	Nucleic acids research
Volume	27
Issue number	10
DOIs	https://doi.org/10.1093/nar/27.10.2063
State	Published - May 15 1999
Externally published	Yes

ASJC Scopus subject areas

Genetics

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title = "Comparative sequence analysis of tmRNA",

abstract = "Minimal secondary structures of the bacterial and plastid tmRNAs were derived by comparative analyses of 50 aligned tmRNA sequences. The structures include 12 helices and four pseudoknots and are refinements of earlier versions, but include only those base pairs for which there is comparative evidence. Described are the conserved and variable features of the tmRNAs from a wide phylogenetic spectrum, the structural properties specific to the bacterial subgroups and preliminary 3-dimensional models from the pseudo-knotted regions.",

author = "Christian Zwieb and Iwona Wower and Jacek Wower",

note = "Funding Information: We thank Drs Florian M{\"u}ller and Richard Brimacombe (Max-Planck Institut f{\"u}r Molekulare Genetic, Berlin, Germany) for providing the ERNA-3D RNA modeling software. This work was supported by a National Institutes of Health grant, GM 58267, to J.W.",

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doi = "10.1093/nar/27.10.2063",

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T1 - Comparative sequence analysis of tmRNA

AU - Zwieb, Christian

AU - Wower, Iwona

AU - Wower, Jacek

N1 - Funding Information: We thank Drs Florian Müller and Richard Brimacombe (Max-Planck Institut für Molekulare Genetic, Berlin, Germany) for providing the ERNA-3D RNA modeling software. This work was supported by a National Institutes of Health grant, GM 58267, to J.W.

PY - 1999/5/15

Y1 - 1999/5/15

N2 - Minimal secondary structures of the bacterial and plastid tmRNAs were derived by comparative analyses of 50 aligned tmRNA sequences. The structures include 12 helices and four pseudoknots and are refinements of earlier versions, but include only those base pairs for which there is comparative evidence. Described are the conserved and variable features of the tmRNAs from a wide phylogenetic spectrum, the structural properties specific to the bacterial subgroups and preliminary 3-dimensional models from the pseudo-knotted regions.

AB - Minimal secondary structures of the bacterial and plastid tmRNAs were derived by comparative analyses of 50 aligned tmRNA sequences. The structures include 12 helices and four pseudoknots and are refinements of earlier versions, but include only those base pairs for which there is comparative evidence. Described are the conserved and variable features of the tmRNAs from a wide phylogenetic spectrum, the structural properties specific to the bacterial subgroups and preliminary 3-dimensional models from the pseudo-knotted regions.

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U2 - 10.1093/nar/27.10.2063

DO - 10.1093/nar/27.10.2063

M3 - Review article

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AN - SCOPUS:0033562579

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SP - 2063

EP - 2071

JO - Nucleic Acids Research

JF - Nucleic Acids Research

IS - 10

ER -

Comparative sequence analysis of tmRNA

Abstract

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