Comparative efficacy in preventing plaque formation around pit and fissure sealants

A clinical trial

Bennett T Amaechi, Hariyali Kasundra, Linda O. Okoye, Phat L. Tran, Ted W. Reid

Research output: Contribution to journalArticle

Abstract

Aim: The purpose of this study is to compare the clinical performance of an organo-selenium-containing pit and fissure sealant with that of a selenium-free sealant for clinical retention and prevention of plaque and caries development around the sealants. Materials and methods: Following an in vitro study confirming the antimicrobial effect of an organo-selenium-containing pit/fissure sealant [DenteShield™ (DS)], 120 adolescents (7-20 years old) at varying caries risk status had DS sealant applied to a single tooth on the left or the right side of the dentition and UltraSeal™ XT Plus (UXT) on a corresponding tooth on the opposite side. Sealants' assessment was performed quarterly for 1 year for clinical retention, plaque, and caries formation around the sealant. Each sealant lost was replaced but considered as a failure in further analysis. McNemar's test was used to statistically analyze the outcome variables at each assessment time point. Results: While 7% and 12% plaque growth was observed around the UXT sealant at 9th and 12th months, respectively, DS exhibited 100% prevention of plaque growth. Both sealants exhibited 100% caries prevention. Clinical retention did not significantly differ between DS and UXT at all assessment time points except at 12 months when DS showed statistically significantly (p < 0.001) better retention (96%) than UXT (81%). Conclusion: In this study, while both sealants are equally effective in caries prevention, DS completely prevented plaque growth around it with better clinical retention than UXT that offered only limited protection against plaque growth.

Original languageEnglish (US)
Pages (from-to)531-536
Number of pages6
JournalJournal of Contemporary Dental Practice
Volume20
Issue number5
DOIs
StatePublished - May 1 2019

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Pit and Fissure Sealants
Clinical Trials
Selenium
Growth
Tooth
Dentition
Ultra Seal XT

Keywords

  • Caries prevention
  • DenteShield™
  • Pit and fissure sealant
  • UltraSeal™ XT Plus™

ASJC Scopus subject areas

  • Dentistry(all)

Cite this

Comparative efficacy in preventing plaque formation around pit and fissure sealants : A clinical trial. / Amaechi, Bennett T; Kasundra, Hariyali; Okoye, Linda O.; Tran, Phat L.; Reid, Ted W.

In: Journal of Contemporary Dental Practice, Vol. 20, No. 5, 01.05.2019, p. 531-536.

Research output: Contribution to journalArticle

Amaechi, Bennett T ; Kasundra, Hariyali ; Okoye, Linda O. ; Tran, Phat L. ; Reid, Ted W. / Comparative efficacy in preventing plaque formation around pit and fissure sealants : A clinical trial. In: Journal of Contemporary Dental Practice. 2019 ; Vol. 20, No. 5. pp. 531-536.
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