Comparative analyses among the Trichomonas vaginalis, Trichomonas tenax, and Tritrichomonas foetus 5S ribosomal RNA genes

Ana Lilia Torres-Machorro, Roberto Hernández, John F. Alderete, Imelda López-Villaseñor

Research output: Contribution to journalReview articlepeer-review

8 Scopus citations

Abstract

The 5S ribosomal RNA (5S rRNA) is an essential component of ribosomes. Throughout evolution, variation is found among 5S rRNA genes regarding their chromosomal localization, copy number, and intergenic regions. In this report, we describe and compare the gene sequences, motifs, genomic copy number, and chromosomal localization of the Trichomonas vaginalis, Trichomonas tenax, and Tritrichomonas foetus 5S rRNA genes. T. vaginalis and T. foetus have a single type of 5S rRNA-coding region, whereas two types were found in T. tenax. The sequence identities among the three organisms are between 94 and 97%. The intergenic regions are more divergent in sequence and size with characteristic species-specific motifs. The T. foetus 5S rRNA gene has larger and more complex intergenic regions, which contain either an ubiquitin gene or repeated sequences. The 5S rRNA genes were located in Trichomonads chromosomes by fluorescent in situ hybridization.

Original languageEnglish (US)
Pages (from-to)199-210
Number of pages12
JournalCurrent Genetics
Volume55
Issue number2
DOIs
StatePublished - 2009
Externally publishedYes

Keywords

  • Chromosome
  • Intergenic region
  • Repeated sequences
  • Ribosome
  • RNA polymerase III
  • Ubiquitin

ASJC Scopus subject areas

  • Genetics

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